Associations of breastfeeding duration with serum lipid values from infancy until age 20 years – the STRIP study

Scand J Public Health. 2023 Jun 30:14034948231183030. doi: 10.1177/14034948231183030. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: The effect of breastfeeding duration on childhood lipid levels has remained controversial. In this study, we aimed to establish the long-term associations of breastfeeding duration with future levels of total cholesterol, high-density lipoprotein…

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Longitudinal patterns of alcohol use and psychological symptoms during COVID-19 pandemic and role of alexithymia: A latent transition analysis in the FinnBrain Birth Cohort Study

J Affect Disord. 2023 Jun 27:S0165-0327(23)00822-4. doi: 10.1016/j.jad.2023.06.056. Online ahead of print. ABSTRACT BACKGROUND: The COVID-19 pandemic has been posing widespread influence on mental well-being. However, research on the dynamic relations between alcohol use and psychological symptoms in the context of the pandemic and the role of alexithymic traits in…

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Associations between temperament dimensions and dental anxiety in parents of the FinnBrain Birth Cohort Study

Eur J Oral Sci. 2022 Dec;130(6):e12897. doi: 10.1111/eos.12897. Epub 2022 Oct 27. ABSTRACT We evaluated associations between dental anxiety and four temperament dimensions: effortful control, extraversion/surgency, negative affect and orienting sensitivity among 2558 parents in the FinnBrain Birth Cohort Study. Dental anxiety was measured with the Modified Dental Anxiety Scale,…

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Dietary fatty acid intake in childhood and the risk of islet autoimmunity and type 1 diabetes: the DIPP birth cohort study

Eur J Nutr. 2023 Mar;62(2):847-856. doi: 10.1007/s00394-022-03035-2. Epub 2022 Oct 25. ABSTRACT PURPOSE: The aim was to study the associations between dietary intake of fatty acids in childhood and the risk of islet autoimmunity and type 1 diabetes (T1D). METHODS: The prospective Finnish Type 1 Diabetes Prediction and Prevention (DIPP)…

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SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis

Nucleic Acids Res. 2022 Nov 11;50(20):11470-11491. doi: 10.1093/nar/gkac900. ABSTRACT Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA turnover pathway that depends on the endonuclease SMG6. Here, we show that SMG6 is essential for male germ cell differentiation in mice. Germ-cell conditional knockout (cKO) of Smg6 induces extensive…

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