Maturitas. 2023 Mar;169:46-52. doi: 10.1016/j.maturitas.2023.01.006. Epub 2023 Jan 18. ABSTRACT AIMS: The prevalence of cardiovascular diseases increases in women after menopause. The aim of the study was to determine the impact of conventional cardiovascular risk factors such as age, blood pressure, smoking, cholesterol, obesity, and glucose balance, but also menopausal…
Publications
Publications
Changes in life satisfaction during the transition to retirement: findings from the FIREA cohort study
Eur J Ageing. 2022 Dec;19(4):1587-1599. doi: 10.1007/s10433-022-00745-8. Epub 2022 Nov 23. ABSTRACT Life satisfaction is an essential construct of well-being that is tied to behavioral, emotional, social and psychological outcomes. This study aimed to examine changes in total and domain-specific life satisfaction during the retirement transition and additionally examine whether…
Work ability and physical fitness among aging workers: the Finnish Retirement and Aging Study
Eur J Ageing. 2022 Dec;19(4):1301-1310. doi: 10.1007/s10433-022-00714-1. Epub 2022 Jun 22. ABSTRACT BACKGROUND: With advancing age, physical capacity gradually decreases which may lead to decreased work ability, if the physical work requirements remain the same. Examination of the importance of physical fitness for work ability among aging workers will help…
Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes until young adulthood: a prospective cohort study
Lancet Child Adolesc Health. 2023 Apr;7(4):261-268. doi: 10.1016/S2352-4642(22)00350-9. Epub 2023 Jan 18. ABSTRACT BACKGROUND: Screening for islet autoantibodies in children and adolescents identifies individuals who will later develop type 1 diabetes, allowing patient and family education to prevent diabetic ketoacidosis at onset and to enable consideration of preventive therapies. We…
Cross-sectionally calculated metabolic ageing does not relate to longitudinal metabolic changes – support for stratified ageing models
J Clin Endocrinol Metab. 2023 Jan 20:dgad032. doi: 10.1210/clinem/dgad032. Online ahead of print. ABSTRACT CONTEXT: Ageing varies between individuals with profound consequences for chronic diseases and longevity. One hypothesis to explain the diversity is a genetically regulated molecular clock that runs differently between individuals. Large and long enough human studies…
Effect of common pregnancy and perinatal complications on offspring metabolic traits across the life course: a multi-cohort study
BMC Med. 2023 Jan 18;21(1):23. doi: 10.1186/s12916-022-02711-8. ABSTRACT BACKGROUND: Common pregnancy and perinatal complications are associated with offspring cardiometabolic risk factors. These complications may influence multiple metabolic traits in the offspring and these associations might differ with offspring age. METHODS: We used data from eight population-based cohort studies to examine…
Course of child social-emotional and sleep symptoms, parental distress and pandemic-related stressors during COVID-19
Dev Psychopathol. 2023 Feb 16:1-15. doi: 10.1017/S0954579422001377. Online ahead of print. ABSTRACT Research on the longitudinal courses of child social-emotional symptoms and sleep during the COVID-19 pandemic within societies would be of key value for promoting child well-being in global crises. We characterized the course of children’s social-emotional and sleep…
Aberrations in the early pregnancy serum metabolic profile in women with prediabetes at two years postpartum
Metabolomics. 2023 Mar 24;19(4):20. doi: 10.1007/s11306-023-01994-z. ABSTRACT INTRODUCTION: Aberrations in circulating metabolites have been associated with diabetes and cardiovascular risk. OBJECTIVES: To investigate if early and late pregnancy serum metabolomic profiles differ in women who develop prediabetes by two years postpartum compared to those who remain normoglycemic. METHODS: An NMR…
Sex differences, asymmetry, and age-related white matter development in infants and 5-year-olds as assessed with tract-based spatial statistics
Hum Brain Mapp. 2023 May;44(7):2712-2725. doi: 10.1002/hbm.26238. Epub 2023 Mar 22. ABSTRACT The rapid white matter (WM) maturation of first years of life is followed by slower yet long-lasting development, accompanied by learning of more elaborate skills. By the age of 5 years, behavioural and cognitive differences between females and…
Stress-Related Exhaustion, Polygenic Cognitive Potential, and Cognitive Test Performance – A General Population Study
Cognit Ther Res. 2023;47(2):155-167. doi: 10.1007/s10608-023-10354-z. Epub 2023 Feb 4. ABSTRACT BACKGROUND: We investigated whether stress-related exhaustion (chronic or short-term, and co-occurring with depression or not) is related to cognitive performance and whether polygenic cognitive potential modifies these associations. METHODS: The participants were from the Young Finns Study (N =…
