JAMA Netw Open. 2023 May 1;6(5):e2312514. doi: 10.1001/jamanetworkopen.2023.12514. ABSTRACT IMPORTANCE: Workplace psychosocial resources naturally tend to cluster in some work teams. To inform work-related sleep health promotion interventions, it is important to determine the associations between clustering of workplace resources and sleep disturbances when some resources are high while others…
Publications
Publications
Gene Set Based Integrated Methylome and Transcriptome Analysis Reveals Potential Molecular Mechanisms Linking Cigarette Smoking and Related Diseases
OMICS. 2023 May;27(5):193-204. doi: 10.1089/omi.2023.0028. Epub 2023 May 5. ABSTRACT Advanced integrative analysis of DNA methylation and transcriptomics data may provide deeper insights into smoke-induced epigenetic alterations, their effects on gene expression and related biological processes, linking cigarette smoking and related diseases. We hypothesize that accumulation of DNA methylation changes…
The relationship of trait-like compassion with epigenetic aging: The population-based prospective Young Finns Study
Front Psychiatry. 2023 Apr 18;14:1018797. doi: 10.3389/fpsyt.2023.1018797. eCollection 2023. ABSTRACT INTRODUCTION: Helping others within and beyond the family has been related to living a healthy and long life. Compassion is a prosocial personality trait characterized by concern for another person who is suffering and the motivation to help. The current…
Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes
J Intern Med. 2023 May 4. doi: 10.1111/joim.13648. Online ahead of print. ABSTRACT The etiology of type 1 diabetes (T1D) foreshadows the pancreatic islet beta-cell autoimmune pathogenesis that heralds the clinical onset of T1D. Standardized and harmonized tests of autoantibodies against insulin (IAA), glutamic acid decarboxylase (GADA), islet antigen-2 (IA-2A),…
Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5-15-Year-Old Children Followed in the TEDDY Study
Diabetes Care. 2023 May 4:dc230036. doi: 10.2337/dc23-0036. Online ahead of print. ABSTRACT OBJECTIVE: This study investigated physical activity and its association with the development of islet autoimmunity and type 1 diabetes in genetically at-risk children aged 5-15 years. RESEARCH DESIGN AND METHODS: As part of the longitudinal Environmental Determinants of…
Comorbidity in congenital hypothyroidism – A nationwide population-based cohort study
J Clin Endocrinol Metab. 2023 Jun 6:dgad334. doi: 10.1210/clinem/dgad334. Online ahead of print. ABSTRACT CONTEXT: Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties. OBJECTIVE: The aim of this nationwide population-based register study was to investigate the incidence of…
Dietary patterns from youth to adulthood and cognitive function in midlife: The cardiovascular risk in Young Finns Study
Nutrition. 2023 Aug;112:112063. doi: 10.1016/j.nut.2023.112063. Epub 2023 Apr 27. ABSTRACT OBJECTIVES: Diet plays an important role in cognitive health, but the long-term association of diet early in life with cognitive function in adulthood has not, to our knowledge, been rigorously studied. The aim of this study was to examine the…
Prediction of pre-diabetes and type 2 diabetes nine years postpartum using serum metabolome in pregnant women with gestational diabetes requiring pharmacological treatment
J Diabetes Complications. 2023 Jul;37(7):108513. doi: 10.1016/j.jdiacomp.2023.108513. Epub 2023 May 26. ABSTRACT AIMS: We examined the association between serum metabolome in women with pharmacologically treated gestational diabetes (GDM) and measures of glucose metabolism 9 years postpartum. METHODS: Serum targeted metabolome, adiponectin, inflammatory markers, and insulin-like growth factor-binding protein-1 phosphoisoforms were…
Hair cortisol, cortisone and DHEA concentrations and the composition of microbiota in toddlers
Psychoneuroendocrinology. 2023 Aug;154:106309. doi: 10.1016/j.psyneuen.2023.106309. Epub 2023 May 25. ABSTRACT Animal research suggests that the gut microbiota and the HPA axis communicate in a bidirectional manner. However, human data, especially on early childhood, remain limited. In this exploratory design, we investigated the connections between long-term HPA axis functioning, measured as…
Childhood trauma and fear of childbirth: findings from a birth cohort study
Arch Womens Ment Health. 2023 May 27. doi: 10.1007/s00737-023-01328-x. Online ahead of print. ABSTRACT The aim of this study is to investigate if experiencing childhood trauma (emotional abuse, emotional neglect, physical abuse, physical neglect, or sexual abuse) or a greater total burden of childhood trauma increase the risk of fear…
