Neuropsychopharmacology. 2025 Jan 31. doi: 10.1038/s41386-025-02059-6. Online ahead of print. ABSTRACT Animal studies have reported associations of early maternal separation with altered μ-opioid receptor function but data on humans are scarce. We now investigated whether childhood family environment is related to μ-opioid receptor availability in the human brain in adulthood.
Publications
Publications
The effect of maternal risk factors during pregnancy on children’s motor development at 5-6 years
Clin Nutr ESPEN. 2025 Jan 25:S2405-4577(25)00048-8. doi: 10.1016/j.clnesp.2025.01.047. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Maternal diet and health may influence a child’s later neurodevelopment. We investigated the effect of maternal diet, adiposity, gestational diabetes mellitus (GDM), and depressive/anxiety symptoms during pregnancy on the child’s motor outcome at 5-6…
Maternal Emotional Availability Supports Child Communicative Development Regardless of Child Temperament-Findings From the FinnBrain Birth Cohort Study
Infancy. 2025 Jan-Feb;30(1):e12649. doi: 10.1111/infa.12649. ABSTRACT The interplay of emotional availability (EA) and child temperament in association with early language development is understudied. We explored associations between maternal EA and infant communicative development and possible moderations by child temperament. Participants were 151 mother-child dyads from the FinnBrain Birth Cohort Study.
Tobacco Smoking in Early Adulthood and Labor Market Performance: The Cardiovascular Risk in Young Finns Study
Nicotine Tob Res. 2025 Jan 14:ntae296. doi: 10.1093/ntr/ntae296. Online ahead of print. ABSTRACT INTRODUCTION: Tobacco smoking has been associated with reduced success in the labor market, potentially due to its negative impact on labor productivity, especially in physically demanding jobs, as it affects physical fitness and performance adversely. METHODS: This…
Outcomes of kidney transplantation in patients with lysinuric protein intolerance
Clin Kidney J. 2024 Nov 22;18(1):sfae373. doi: 10.1093/ckj/sfae373. eCollection 2025 Jan. ABSTRACT BACKGROUND: Lysinuric protein intolerance (LPI) is a metabolic disorder that leads to dysfunctional intestinal absorption and kidney clearance of cationic amino acids. Chronic kidney disease develops in many LPI patients and leads to end-stage kidney disease in at…
Gestational Duration and Postnatal Age-Related Changes in Aperiodic and Periodic Parameters in Neonatal and Toddler Electroencephalogram (EEG)
Hum Brain Mapp. 2025 Jan;46(1):e70130. doi: 10.1002/hbm.70130. ABSTRACT The brain develops most rapidly during pregnancy and early neonatal months. While prior electrophysiological studies have shown that aperiodic brain activity undergoes changes across infancy to adulthood, the role of gestational duration in aperiodic and periodic activity remains unknown. In this study,…
Exposure to childhood maltreatment is associated with specific epigenetic patterns in sperm
Mol Psychiatry. 2025 Jan 3. doi: 10.1038/s41380-024-02872-3. Online ahead of print. ABSTRACT Childhood maltreatment exposure (CME) increases the risk of adverse long-term health consequences for the exposed individual. Animal studies suggest that CME may also influence the health and behaviour in the next generation offspring through CME-driven epigenetic changes in…
Association Between the Two-Year Trajectories of Dental Anxiety and the Changes in the Oral Health-Related Quality of Life in Parents of FinnBrain Birth Cohort Study
Dent J (Basel). 2024 Dec 6;12(12):398. doi: 10.3390/dj12120398. ABSTRACT Objectives: We evaluated associations between changes in dental anxiety and oral health-related quality of life (OHRQoL) in parents of the FinnBrain Birth Cohort Study. Methods: Two-year dental anxiety trajectories measured with Modified Dental Anxiety Scale from gestational weeks (gw) 14 and…
Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms
Anal Chem. 2024 Dec 16. doi: 10.1021/acs.analchem.4c03229. Online ahead of print. ABSTRACT Applications of advanced omics methodologies are increasingly popular in biomedicine. However, large-scale studies aiming at clinical translation are typically siloed to single technologies. Here, we present the first comprehensive large-scale population data combining 209 lipoprotein measures from a…
Understanding lipidomics associations and the lipoprotein-related caveats in population epidemiology
Am J Epidemiol. 2024 Nov 28:kwae445. doi: 10.1093/aje/kwae445. Online ahead of print. ABSTRACT Mass spectrometry lipidomics is becoming customary to analyse serum/plasma samples in epidemiology. The measurables are molecular constituents of lipoprotein particles, but very little is known on the consequences of adjusting lipidomics data with lipoprotein measures. We studied…
