Med Sci Sports Exerc. 2024 Nov 6. doi: 10.1249/MSS.0000000000003594. Online ahead of print. ABSTRACT Purpose: The associations between work time, leisure-time, and non-workday physical activity (PA) and sedentary behavior (SED) and 24 h ambulatory blood pressure (BP) are not well known. Therefore, the aim of this study was to evaluate…
Publications
Publications
Sex-specific associations between maternal prenatal inflammation and offspring cortical morphology in youth: A harmonised study across four birth cohorts
Brain Behav Immun. 2024 Nov 4:S0889-1591(24)00692-5. doi: 10.1016/j.bbi.2024.11.010. Online ahead of print. ABSTRACT Maternal immune activation (MIA) during pregnancy is implicated in offspring psychiatric disorders. However, it is unknown to what extent MIA affects neurodevelopment, particularly cerebrocortical anatomy, in the general population, and whether effects differ by sex. The current…
Device-Measured 24-Hour Movement Behaviors and Blood Pressure: A 6-Part Compositional Individual Participant Data Analysis in the ProPASS Consortium
Circulation. 2024 Nov 6. doi: 10.1161/CIRCULATIONAHA.124.069820. Online ahead of print. ABSTRACT BACKGROUND: Blood pressure (BP)-lowering effects of structured exercise are well-established. Effects of 24-hour movement behaviors captured in free-living settings have received less attention. This cross-sectional study investigated associations between a 24-hour behavior composition comprising 6 parts (sleeping, sedentary behavior,…
Maternal alexithymia and caregiving behavior: the role of executive functioning – A FinnBrain Birth Cohort study
Arch Womens Ment Health. 2024 Nov 5. doi: 10.1007/s00737-024-01523-4. Online ahead of print. ABSTRACT PURPOSE: The growing interest in parental cognition calls for research clarifying how cognition interacts with other parenting determinants to shape caregiving behavior. We studied the interplay between executive functioning (EF; cognitive processes that enable goal-directed thinking…
Looking back at the TEDDY study: lessons and future directions
Nat Rev Endocrinol. 2024 Nov 4. doi: 10.1038/s41574-024-01045-0. Online ahead of print. ABSTRACT The goal of the TEDDY (The Environmental Determinants of Diabetes in the Young) study is to elucidate factors leading to the initiation of islet autoimmunity (first primary outcome) and those related to progression to type 1 diabetes…
Tracking and Transition Probability of Blood Pressure From Childhood to Midadulthood
JAMA Pediatr. 2024 Nov 4. doi: 10.1001/jamapediatrics.2024.4368. Online ahead of print. ABSTRACT IMPORTANCE: Despite its relevance for pediatric blood pressure (BP) screening, the long-term predictive utility and natural progression of pediatric BP classification remain understudied. OBJECTIVE: To evaluate BP tracking from childhood to midadulthood using the American Academy of Pediatrics…
The role of early life factors and green living environment in the development of gut microbiota in infancy: Population-based cohort study
Environ Int. 2024 Oct 22;193:109093. doi: 10.1016/j.envint.2024.109093. Online ahead of print. ABSTRACT OBJECTIVE: Early life microbial exposure influences the composition of gut microbiota. We investigated how early life factors, and the green living environment around infants’ homes, influence the development of gut microbiota during infancy by utilizing data from the…
Higher initial levothyroxine doses and very early treatment start may lead to better cognitive outcomes in children with congenital hypothyroidism
Acta Paediatr. 2024 Nov 1. doi: 10.1111/apa.17479. Online ahead of print. ABSTRACT AIM: This study aimed to assess the cognitive development of individuals with congenital hypothyroidism. METHODS: Using hospital records, we identified 180 patients with congenital hypothyroidism born between 1980 and 2018 in Turku and Kuopio University Hospital catchment areas.
Simulated ischaemia/reperfusion impairs trophoblast function through divergent oxidative stress- and MMP-9-dependent mechanisms
Biosci Rep. 2024 Oct 30:BSR20240763. doi: 10.1042/BSR20240763. Online ahead of print. ABSTRACT Early-onset pre-eclampsia is believed to arise from defective placentation in the 1st trimester, leading to placental ischaemia/reperfusion (I/R) and oxidative stress. However, our current understanding of the effects of I/R and oxidative stress on trophoblast function is ambiguous…
Changes in 24-h Movement Behaviors During Relationship and Parenthood Transitions: A Compositional Data Analysis
Scand J Med Sci Sports. 2024 Nov;34(11):e14751. doi: 10.1111/sms.14751. ABSTRACT There is scarcity of studies using device-based measures to examine how relationship and parenthood transitions modify 24-h movement behaviors. This study examined how the composition of 24-h movement behaviors changes during these life transitions. Young adults (n = 170, mean…
