Association of cumulative prenatal adversity with infant subcortical structure volumes and child problem behavior and its moderation by a coexpression polygenic risk score of the serotonin system

Dev Psychopathol. 2023 Apr 3:1-16. doi: 10.1017/S0954579423000275. Online ahead of print. ABSTRACT Prenatal adversity has been linked to later psychopathology. Yet, research on cumulative prenatal adversity, as well as its interaction with offspring genotype, on brain and behavioral development is scarce. With this study, we aimed to address this gap.

Association of Sit-to-Stand Capacity and Free-Living Performance Using Thigh-Worn Accelerometers among 60-90-Year-Old Adults

Med Sci Sports Exerc. 2023 Apr 3. doi: 10.1249/MSS.0000000000003178. Online ahead of print. ABSTRACT PURPOSE: Five times sit-to-stand (STS) test is commonly used as a clinical assessment of lower-extremity functional ability, but its association with free-living performance has not been studied. Therefore, we investigated the association between laboratory-based STS capacity…

Higher attention bias for fear at 8 months of age is associated with better socioemotional competencies during toddlerhood

Infant Behav Dev. 2023 May;71:101838. doi: 10.1016/j.infbeh.2023.101838. Epub 2023 Mar 28. ABSTRACT BACKGROUND: In previous studies, an attention bias for signals of fear and threat has been related to socioemotional problems, such as anxiety symptoms, and socioemotional competencies, such as altruistic behaviors in children, adolescents and adults. However, previous studies…

Exposure to Phthalates in European Children, Adolescents and Adults since 2005: A Harmonized Approach Based on Existing HBM Data in the HBM4EU Initiative

Toxics. 2023 Mar 4;11(3):241. doi: 10.3390/toxics11030241. ABSTRACT Phthalates are mainly used as plasticizers and are associated inter alia with adverse effects on reproductive functions. While more and more national programs in Europe have started monitoring internal exposure to phthalates and its substitute 1,2-Cyclohexanedicarboxylic acid (DINCH), the comparability of results from…

Pre- and postnatal maternal depressive symptoms associate with white matter integrity in 5-year-olds in sex-specific manner

Biol Psychiatry. 2023 May 21:S0006-3223(23)01301-X. doi: 10.1016/j.biopsych.2023.05.014. Online ahead of print. ABSTRACT BACKGROUND: Pre- and postnatal maternal psychological distress predicts various detrimental consequences on social, behavioural, and cognitive development of the offspring and especially in girls. Maturation of white matter (WM) continues from prenatal development into adulthood and is thus…

Tracking of Cardiorespiratory Fitness and Physical Activity from Youth to Young Adulthood: Findings from the Prospective Special Turku Coronary Risk Factor Intervention Project (STRIP)

J Pediatr X. 2023 Feb 28;9:100085. doi: 10.1016/j.ympdx.2023.100085. eCollection 2023 Summer. ABSTRACT Using data from the Special Turku Coronary Risk Factor Intervention Project, cardiorespiratory fitness (rank-order correlation coefficient = 0.60-0.62) tracked stronger than physical activity (rank-order correlation coefficient = 0.27-0.38) between youth (age = 17 years) and young adulthood (age…

Metformin versus insulin for gestational diabetes: Adiposity variables and adipocytokines in offspring at age of 9 years

Diabetes Res Clin Pract. 2023 Jun 16:110780. doi: 10.1016/j.diabres.2023.110780. Online ahead of print. ABSTRACT AIMS: To compare body composition, visceral adiposity, adipocytokines, and low-grade inflammation markers in prepubertal offspring of mothers who were treated with metformin or insulin for gestational diabetes mellitus (GDM). METHODS: 172 offspring of 311 mothers randomized…

Neighbourhood deprivation in childhood and adulthood and risk of arterial stiffness: the Cardiovascular Risk in Young Finns study

Blood Press. 2023 Dec;32(1):2220037. doi: 10.1080/08037051.2023.2220037. ABSTRACT Purpose: Individual socioeconomic status is associated with increased arterial stiffness, but limited data are available on the relations of neighbourhood deprivation with this vascular measure. We prospectively examined whether neighbourhood deprivation in childhood and adulthood predicts arterial stiffness indicated by pulse wave velocity…

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