Lancet Child Adolesc Health. 2023 Apr;7(4):261-268. doi: 10.1016/S2352-4642(22)00350-9. Epub 2023 Jan 18. ABSTRACT BACKGROUND: Screening for islet autoantibodies in children and adolescents identifies individuals who will later develop type 1 diabetes, allowing patient and family education to prevent diabetic ketoacidosis at onset and to enable consideration of preventive therapies. We…

J Clin Endocrinol Metab. 2023 Jan 20:dgad032. doi: 10.1210/clinem/dgad032. Online ahead of print. ABSTRACT CONTEXT: Ageing varies between individuals with profound consequences for chronic diseases and longevity. One hypothesis to explain the diversity is a genetically regulated molecular clock that runs differently between individuals. Large and long enough human studies…

BMC Med. 2023 Jan 18;21(1):23. doi: 10.1186/s12916-022-02711-8. ABSTRACT BACKGROUND: Common pregnancy and perinatal complications are associated with offspring cardiometabolic risk factors. These complications may influence multiple metabolic traits in the offspring and these associations might differ with offspring age. METHODS: We used data from eight population-based cohort studies to examine…

Dev Psychopathol. 2023 Feb 16:1-15. doi: 10.1017/S0954579422001377. Online ahead of print. ABSTRACT Research on the longitudinal courses of child social-emotional symptoms and sleep during the COVID-19 pandemic within societies would be of key value for promoting child well-being in global crises. We characterized the course of children’s social-emotional and sleep…

BMC Med. 2023 Feb 14;21(1):57. doi: 10.1186/s12916-023-02743-8. ABSTRACT BACKGROUND: An extensive body of animal literature supports the premise that maternal obesity during pregnancy can alter the development of the fetal hypothalamus (HTH, a critical regulator of energy balance) with implications for offspring obesity risk (i.e., long-term energy imbalance). Yet, the…

Sci Rep. 2023 Feb 9;13(1):2303. doi: 10.1038/s41598-023-29381-7. ABSTRACT Children have special rights for protection compared to adults in our society. However, more than 1/4 of children globally have no documentation of their date of birth. Hence, there is a pressing need to develop biological methods for chronological age prediction, robust…

Front Psychol. 2023 Jan 19;14:1067872. doi: 10.3389/fpsyg.2023.1067872. eCollection 2023. ABSTRACT BACKGROUND: It has long been suggested that addictive behaviors are associated with alexithymia, a personality trait characterized by difficulties in emotional awareness and expression. However, little is known about the role of alexithymia in food addiction. OBJECTIVES: The aim of…

Sci Total Environ. 2023 May 1;871:161914. doi: 10.1016/j.scitotenv.2023.161914. Epub 2023 Jan 31. ABSTRACT BACKGROUND: Phthalate exposure during fetal life may disrupt testicular development. Congruent with this, studies have found shorter anogenital distance, reduced penile size and altered hormone levels in infant boys whose mothers were exposed to higher levels of…

PLoS One. 2023 Feb 2;18(2):e0275123. doi: 10.1371/journal.pone.0275123. eCollection 2023. ABSTRACT BACKGROUND: Celiac disease has an increasing incidence worldwide and is treated with lifelong adherence to a gluten-free diet. We aimed to describe gluten-free diet adherence rates in children with screening-identified celiac disease, determine adherence-related factors, and compare adherence to food…

Med Sci Sports Exerc. 2023 May 1;55(5):837-846. doi: 10.1249/MSS.0000000000003108. Epub 2022 Dec 27. ABSTRACT PURPOSE: This study aimed to identify physical activity patterns and examine their association with cardiometabolic biomarkers in a cross-sectional design. METHODS: Overall 6072 participants (mean age, 60.2 yr; SD 8.6 yr, 50% women) from The Maastricht…