Pediatr Diabetes. 2025 Sep 16;2025:8845330. doi: 10.1155/pedi/8845330. eCollection 2025. ABSTRACT Objective: To design a dynamic prediction model for estimating the time of progression from a single glutamic acid decarboxylase autoantibody (GADA) to multiple islet autoantibodies and type 1 diabetes in children, exploring different longitudinally measured risk variables. Research Design and…
Publications
Publications
Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis
Arthritis Rheumatol. 2025 Jul 16. doi: 10.1002/art.43315. Online ahead of print. ABSTRACT OBJECTIVE: Patients with juvenile idiopathic arthritis (JIA) frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in patients with JIA remains elusive. METHODS: Plasma samples from 110…
Infant temperament predicts early communicative skills in the FinnBrain Birth Cohort Study
J Commun Disord. 2025 Sep 4;118:106564. doi: 10.1016/j.jcomdis.2025.106564. Online ahead of print. ABSTRACT Studies have established that dimensions of temperament and language development are associated in childhood. Insofar, however, longitudinal studies from infancy into toddlerhood accounting for all temperament dimensions and covering preverbal communication in addition to emerging verbal skills…
Corrigendum to: A Clinical Tool to Relate Youth Risk Factors to Adult Cardiovascular Events and Type 2 Diabetes: The i3C Consortium J. Pediatr. 2025 Jan;276:114277
J Pediatr. 2025 Sep 12:114782. doi: 10.1016/j.jpeds.2025.114782. Online ahead of print. NO ABSTRACT PMID:40946039 | DOI:10.1016/j.jpeds.2025.114782…
The effect of polychlorinated biphenyls on type 2 diabetes risk is mediated via DNA methylation
Environ Int. 2025 Sep 3;203:109779. doi: 10.1016/j.envint.2025.109779. Online ahead of print. ABSTRACT Polychlorinated biphenyls (PCBs) have been identified as diabetogens and potential epigenetic regulators. Epigenetic variation is implicated in the pathogenesis of type 2 diabetes (T2D) and is therefore a potential mechanism linking PCB exposure and T2D. We here investigate…
Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium
Mol Psychiatry. 2025 Sep 6. doi: 10.1038/s41380-025-03203-w. Online ahead of print. ABSTRACT Epigenetic processes, such as DNA methylation, show potential as biological markers and mechanisms underlying gene-environment interplay in the prediction of mental health and other brain-based phenotypes. However, little is known about how peripheral epigenetic patterns relate to individual…
Pre- and postnatal maternal depressive symptoms associate with local connectivity of the left amygdala in 5-year-olds
Eur Psychiatry. 2025 Sep 5:1-29. doi: 10.1192/j.eurpsy.2025.10097. Online ahead of print. NO ABSTRACT PMID:40908266 | DOI:10.1192/j.eurpsy.2025.10097…
Continuity and Changes in Work Commuting Modes and Their Associations With Overall Physical Activity and Weight Status Among Finnish Adults
J Phys Act Health. 2025 Aug 19:1-9. doi: 10.1123/jpah.2024-0644. Online ahead of print. ABSTRACT BACKGROUND: This paper aims to examine and compare the levels and changes in physical activity (PA) and weight status over an 11-year follow-up among adults with varying commuting modes to work. METHODS: Overall, 1357 Finnish adults…
Concurrent changes in sleep and cognitive function during retirement transition: the Finnish retirement and aging study
Eur J Ageing. 2025 Aug 7;22(1):40. doi: 10.1007/s10433-025-00876-8. ABSTRACT The transition to retirement has been shown to be accompanied by increased sleep duration and improved sleep quality. In addition, some studies suggest accelerated decline in cognitive function in post-retirement years. However, less is known about their interconnectedness. The aim of…
Device-Measured Sleep Characteristics, Daily Step Count, and Cardiometabolic Health Markers: Findings From the Prospective Physical Activity, Sitting, and Sleep (ProPASS) Consortium
Circ Cardiovasc Qual Outcomes. 2025 Jul 24:e011873. doi: 10.1161/CIRCOUTCOMES.124.011873. Online ahead of print. ABSTRACT BACKGROUND: Sleep and physical activity (PA) are important lifestyle-related behaviors that impact cardiometabolic health. This study investigated the joint associations of daily step count and sleep patterns (regularity and duration) with cardiometabolic biomarkers in adults. METHODS:…
