Publications

Pediatr Diabetes. 2023;2023:3945064. doi: 10.1155/2023/3945064. Epub 2023 Feb 17. ABSTRACT BACKGROUND/OBJECTIVE: Growth and obesity have been associated with increased risk of islet autoimmunity (IA) and progression to type 1 diabetes. We aimed to estimate the effect of energy-yielding macronutrient intake on the development of IA through BMI. RESEARCH DESIGN AND…

Diabetes Care. 2023 Aug 22:dc230518. doi: 10.2337/dc23-0518. Online ahead of print. ABSTRACT OBJECTIVE: To investigate gastrointestinal infection episodes (GIEs) in relation to the appearance of islet autoantibodies in The Environmental Determinants of Diabetes in the Young (TEDDY) cohort. RESEARCH DESIGN AND METHODS: GIEs on risk of autoantibodies against either insulin…

Hum Brain Mapp. 2023 Aug 22. doi: 10.1002/hbm.26463. Online ahead of print. ABSTRACT Non-verbal cognitive ability predicts multiple important life outcomes, for example, school and job performance. It has been associated with parieto-frontal cortical anatomy in prior studies in adult and adolescent populations, while young children have received relatively little…

Diabetes Care. 2023 Aug 14:dc230417. doi: 10.2337/dc23-0417. Online ahead of print. ABSTRACT OBJECTIVE: To study the interaction among HLA genotype, early probiotic exposure, and timing of complementary foods in relation to risk of islet autoimmunity (IA). RESEARCH DESIGN AND METHODS: The TEDDY study prospectively follows 8,676 children with increased genetic…

Psychoneuroendocrinology. 2023 Jul 29;156:106345. doi: 10.1016/j.psyneuen.2023.106345. Online ahead of print. ABSTRACT This study performed latent profile analysis from more than 4000 saliva cortisol samples collected from children at the ages of 2 (T1), 3.5 (T2), and 5 years (T3). Three clearly different cortisol profiles were identified. The largest group at…

Eur J Ageing. 2023 Aug 3;20(1):32. doi: 10.1007/s10433-023-00779-6. ABSTRACT STUDY OBJECTIVES: Sleep duration has been shown to associate with cognitive function, but little is known about the short-term effect of sleep duration on the previous night. This study examines how usual sleep duration and previous night’s sleep duration are associated…

Nat Commun. 2023 Aug 2;14(1):4646. doi: 10.1038/s41467-023-39521-2. ABSTRACT Resting heart rate is associated with cardiovascular diseases and mortality in observational and Mendelian randomization studies. The aims of this study are to extend the number of resting heart rate associated genetic variants and to obtain further insights in resting heart rate…

N Engl J Med. 2023 Aug 3;389(5):474-475. doi: 10.1056/NEJMc2216477. NO ABSTRACT PMID:37530831 | DOI:10.1056/NEJMc2216477…

Psychiatry Res. 2023 Jul 17;326:115355. doi: 10.1016/j.psychres.2023.115355. Online ahead of print. ABSTRACT We investigated whether individuals, who have a high polygenic loading for schizophrenia and major depression (PGL) but have not developed the respective disorders, are still susceptible to experience milder forms of ill-being in terms of job strain or…

J Clin Endocrinol Metab. 2023 Jul 18:dgad418. doi: 10.1210/clinem/dgad418. Online ahead of print. ABSTRACT BACKGROUND & AIMS: The incidence and remission of non-alcoholic fatty liver disease (NAFLD) are sparsely studied outside Asia. This prospective study aimed to investigate NAFLD incidence and remission, and their predictors among a general Finnish population.