Publications

Scand J Med Sci Sports. 2023 May;33(5):682-692. doi: 10.1111/sms.14293. Epub 2023 Jan 4. ABSTRACT This study examined longitudinal associations between parenthood-related factors and physical activity from young adulthood to midlife over a 19-year follow-up period. Participants (n = 761) at the ongoing Cardiovascular Risk in Young Finns Study responded to…

Genome Biol. 2022 Dec 27;23(1):268. doi: 10.1186/s13059-022-02837-1. ABSTRACT BACKGROUND: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery.

Front Endocrinol (Lausanne). 2022 Dec 9;13:1071761. doi: 10.3389/fendo.2022.1071761. eCollection 2022. ABSTRACT INTRODUCTION: Environmental exposure during fetal life may disrupt testicular development. In humans, a limited number of studies have investigated whether these adverse effects persist into adulthood. Using data from a prospective, population-based birth cohort study, The Copenhagen Mother-Child cohort,…

Int J Mol Sci. 2022 Dec 11;23(24):15726. doi: 10.3390/ijms232415726. ABSTRACT Only 3-5% of heavy alcohol users develop acute alcohol pancreatitis (AAP). This suggests that additional triggers are required to initiate the inflammatory process. Genetic susceptibility contributes to the development of AAP, and SPINK1 mutation is a documented risk factor. We…

Maturitas. 2023 Mar;169:46-52. doi: 10.1016/j.maturitas.2023.01.006. Epub 2023 Jan 18. ABSTRACT AIMS: The prevalence of cardiovascular diseases increases in women after menopause. The aim of the study was to determine the impact of conventional cardiovascular risk factors such as age, blood pressure, smoking, cholesterol, obesity, and glucose balance, but also menopausal…

Eur J Ageing. 2022 Dec;19(4):1587-1599. doi: 10.1007/s10433-022-00745-8. Epub 2022 Nov 23. ABSTRACT Life satisfaction is an essential construct of well-being that is tied to behavioral, emotional, social and psychological outcomes. This study aimed to examine changes in total and domain-specific life satisfaction during the retirement transition and additionally examine whether…

Eur J Ageing. 2022 Dec;19(4):1301-1310. doi: 10.1007/s10433-022-00714-1. Epub 2022 Jun 22. ABSTRACT BACKGROUND: With advancing age, physical capacity gradually decreases which may lead to decreased work ability, if the physical work requirements remain the same. Examination of the importance of physical fitness for work ability among aging workers will help…

Lancet Child Adolesc Health. 2023 Apr;7(4):261-268. doi: 10.1016/S2352-4642(22)00350-9. Epub 2023 Jan 18. ABSTRACT BACKGROUND: Screening for islet autoantibodies in children and adolescents identifies individuals who will later develop type 1 diabetes, allowing patient and family education to prevent diabetic ketoacidosis at onset and to enable consideration of preventive therapies. We…

J Clin Endocrinol Metab. 2023 Jan 20:dgad032. doi: 10.1210/clinem/dgad032. Online ahead of print. ABSTRACT CONTEXT: Ageing varies between individuals with profound consequences for chronic diseases and longevity. One hypothesis to explain the diversity is a genetically regulated molecular clock that runs differently between individuals. Large and long enough human studies…

BMC Med. 2023 Jan 18;21(1):23. doi: 10.1186/s12916-022-02711-8. ABSTRACT BACKGROUND: Common pregnancy and perinatal complications are associated with offspring cardiometabolic risk factors. These complications may influence multiple metabolic traits in the offspring and these associations might differ with offspring age. METHODS: We used data from eight population-based cohort studies to examine…