Author: Henok Karvonen

Atherosclerosis. 2025 May 21;406:120218. doi: 10.1016/j.atherosclerosis.2025.120218. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Comprehensive longitudinal data in healthy populations on cardiometabolic determinants of arterial intima-media thickness (IMT), especially aortic IMT, in adolescence are lacking. We aimed to examine in detail how cardiometabolic risk factors associate with aortic and carotid…

Schizophr Res. 2025 May 23;281:229-236. doi: 10.1016/j.schres.2025.05.017. Online ahead of print. ABSTRACT BACKGROUND: A high genetic risk for schizophrenia, in complex interplay with environmental factors, has been suggested to explain population-level variation in personality traits among individuals who do not develop schizophrenia-spectrum disorders. We investigated, first, whether polygenic risk for…

Acta Paediatr. 2025 May 23. doi: 10.1111/apa.70148. Online ahead of print. ABSTRACT AIM: As earlier puberty has been associated with higher later metabolic risk, we studied how weight gain in infancy and childhood is associated with pubertal timing and duration in healthy children. METHOD: Leveraging the longitudinal data from the…

Med Sci Sports Exerc. 2025 May 21. doi: 10.1249/MSS.0000000000003760. Online ahead of print. ABSTRACT PURPOSE: To examine the tracking and trajectories of active commuting (AC) from childhood to midlife and their association with physical activity (PA) levels over 35 years. METHODS: Self-rated AC and PA data were extracted from the…

Am J Epidemiol. 2025 May 14:kwaf106. doi: 10.1093/aje/kwaf106. Online ahead of print. ABSTRACT In this prospective cohort study, we explored associations of childhood socioeconomic status (SES) with social connection in adulthood, and to which extent these associations can be explained by SES in adulthood. We used data from the longitudinal…

J Nutr. 2025 May 12:S0022-3166(25)00287-1. doi: 10.1016/j.tjnut.2025.05.005. Online ahead of print. ABSTRACT BACKGROUND: Stability in dietary habits has been observed during childhood and adolescence, but their stability from infancy to adulthood is less known. OBJECTIVES: Our aim was to identify latent diet quality trajectories from age 1 to 18 years…

Eur Heart J Open. 2025 Apr 16;5(3):oeaf038. doi: 10.1093/ehjopen/oeaf038. eCollection 2025 May. ABSTRACT AIMS: Prevalence of cardiovascular diseases (CVDs) and depression is rising globally. Their co-occurrence associates with poorer outcomes, potentially due to shared metabolic pathways. This study aimed to identify metabolic pathways linking depression symptoms and CVD risk factors.

Psychol Med. 2025 May 2;55:e133. doi: 10.1017/S0033291725000911. ABSTRACT BACKGROUND: Previous evidence has reported associations of a polygenic risk score for schizophrenia (PRSSCZ) with negative developmental outcomes, such as psychiatric symptoms, adverse health behaviors, and reduced everyday functioning. We now investigated the relationship of PRSSCZ with subjectively experienced well-being. METHODS: Participants…

Pediatr Diabetes. 2023 Dec 11;2023:9973135. doi: 10.1155/2023/9973135. eCollection 2023. ABSTRACT OBJECTIVE: We studied the characteristics of children who developed islet autoantibodies by the age of 0.50 years and hypothesized that the appearance of extremely early islet autoimmunity differs between four birth cohorts within 1994-2019 according to the change in the…

Clin Epigenetics. 2025 Apr 29;17(1):68. doi: 10.1186/s13148-025-01871-7. ABSTRACT Non-coding 886 (nc886, vtRNA2-1) is a polymorphically imprinted gene. The methylation status of this locus has been shown to be associated with periconceptional conditions, and both the methylation status and the levels of nc886 RNAs have been shown to associate with later-life…