Author: Henok Karvonen

EJHaem. 2022 Sep 29;3(4):1188-1200. doi: 10.1002/jha2.588. eCollection 2022 Nov. ABSTRACT Cancer survivors show increased risk for non-communicable diseases and chronic low-grade inflammation characterizes the development of such diseases. We investigated inflammatory plasma protein profiles of survivors of childhood acute lymphoblastic leukemia (ALL) in comparison to healthy controls and after an…

Prog Neuropsychopharmacol Biol Psychiatry. 2023 Apr 20;123:110720. doi: 10.1016/j.pnpbp.2023.110720. Epub 2023 Jan 14. ABSTRACT Recent advances in genome-wide association studies have enabled the estimation of genetic risk of complex traits, including neuroticism, with polygenic risk scores (PRS). Neuroticism PRS has been associated with psychiatric disorders and symptoms in adults, but…

Endocrinology. 2022 Dec 19;164(2):bqac202. doi: 10.1210/endocr/bqac202. ABSTRACT Spermatogenesis is a complex differentiation process that takes place in the seminiferous tubules. A specific organization of spermatogenic cells within the seminiferous epithelium enables a synchronous progress of germ cells at certain steps of differentiation on the spermatogenic pathway. This can be observed…

Andrology. 2023 May;11(4):710-723. doi: 10.1111/andr.13361. Epub 2023 Jan 9. ABSTRACT BACKGROUND: Germ granules are large cytoplasmic ribonucleoprotein complexes that emerge in the germline to participate in RNA regulation. The two most prominent germ granules are the intermitochondrial cement (IMC) in meiotic spermatocytes and the chromatoid body (CB) in haploid round…

Sci Rep. 2022 Dec 2;12(1):20818. doi: 10.1038/s41598-022-25336-6. ABSTRACT While sunlight may influence cognitive function through several pathways, associations of residential sunlight exposure with cognitive function are not well known. We evaluated associations of long-term residential sunlight exposure with cognitive function among a representative cohort of 1838 Finnish adults residing in…

Best Pract Res Clin Obstet Gynaecol. 2023 Feb;86:102298. doi: 10.1016/j.bpobgyn.2022.102298. Epub 2022 Dec 17. ABSTRACT Semen quality has declined especially among Western men. Experimental and epidemiological studies have shown potential links between exposure to environmental toxicants and poor male fertility. Some environmental exposures in utero can disrupt fetal testicular function…

Eur J Neurosci. 2023 Jan;57(2):242-257. doi: 10.1111/ejn.15882. Epub 2022 Dec 17. ABSTRACT Prenatal stress exposure (PSE) has been observed to exert a programming effect on the developing infant brain, possibly with long-lasting consequences on temperament, cognitive functions and the risk for developing psychiatric disorders. Several prior studies have revealed that…

Sci Rep. 2023 Jan 5;13(1):216. doi: 10.1038/s41598-022-27317-1. ABSTRACT Increased exposure to greener environments has been suggested to lead to health benefits in children, but the associated mechanisms in early life, particularly via biological mediators such as altered maternal milk composition, remain largely unexplored. We investigated the associations between properties of…

Eur J Oral Sci. 2023 Feb;131(1):e12912. doi: 10.1111/eos.12912. Epub 2023 Jan 4. ABSTRACT We evaluated associations between changes in dental anxiety and tobacco use, adjusted for general anxiety and depressive symptoms. The FinnBrain Birth Cohort Study data, collected at gestational weeks 14 and 34 and at 3 months postpartum, were…

PLoS One. 2023 Feb 2;18(2):e0275123. doi: 10.1371/journal.pone.0275123. eCollection 2023. ABSTRACT BACKGROUND: Celiac disease has an increasing incidence worldwide and is treated with lifelong adherence to a gluten-free diet. We aimed to describe gluten-free diet adherence rates in children with screening-identified celiac disease, determine adherence-related factors, and compare adherence to food…