Author: Henok Karvonen

Infancy. 2025 Jan-Feb;30(1):e12649. doi: 10.1111/infa.12649. ABSTRACT The interplay of emotional availability (EA) and child temperament in association with early language development is understudied. We explored associations between maternal EA and infant communicative development and possible moderations by child temperament. Participants were 151 mother-child dyads from the FinnBrain Birth Cohort Study.

Nicotine Tob Res. 2025 Jan 14:ntae296. doi: 10.1093/ntr/ntae296. Online ahead of print. ABSTRACT INTRODUCTION: Tobacco smoking has been associated with reduced success in the labor market, potentially due to its negative impact on labor productivity, especially in physically demanding jobs, as it affects physical fitness and performance adversely. METHODS: This…

Clin Kidney J. 2024 Nov 22;18(1):sfae373. doi: 10.1093/ckj/sfae373. eCollection 2025 Jan. ABSTRACT BACKGROUND: Lysinuric protein intolerance (LPI) is a metabolic disorder that leads to dysfunctional intestinal absorption and kidney clearance of cationic amino acids. Chronic kidney disease develops in many LPI patients and leads to end-stage kidney disease in at…

2023 Mar 29. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New…

J Hypertens. 2023 Jan 1;41(1):187-193. doi: 10.1097/HJH.0000000000003320. Epub 2022 Oct 27. ABSTRACT OBJECTIVES: Retirement is a major life event characterized by removal of work-related stressors and changes in health behaviours. The association between retirement and changes in blood pressure (BP), and particularly in ambulatory BP, has been scarcely studied. We…

Eur J Oral Sci. 2022 Dec;130(6):e12897. doi: 10.1111/eos.12897. Epub 2022 Oct 27. ABSTRACT We evaluated associations between dental anxiety and four temperament dimensions: effortful control, extraversion/surgency, negative affect and orienting sensitivity among 2558 parents in the FinnBrain Birth Cohort Study. Dental anxiety was measured with the Modified Dental Anxiety Scale,…

Dis Model Mech. 2022 Oct 1;15(10):dmm049490. doi: 10.1242/dmm.049490. Epub 2022 Oct 26. ABSTRACT Isolated populations have been valuable for the discovery of rare monogenic diseases and their causative genetic variants. Finnish disease heritage (FDH) is an example of a group of hereditary monogenic disorders caused by single major, usually autosomal-recessive,…

Nordisk Alkohol Nark. 2022 Oct;39(5):568-584. doi: 10.1177/14550725221096908. Epub 2022 Jun 9. ABSTRACT Background and aim: Use of nicotine can harm adolescents’ brains and increase risk for future addiction to other drugs. Several international studies show that an acceptable attitude towards nicotine products increases the initiation or use of the products.

Eur J Nutr. 2023 Mar;62(2):847-856. doi: 10.1007/s00394-022-03035-2. Epub 2022 Oct 25. ABSTRACT PURPOSE: The aim was to study the associations between dietary intake of fatty acids in childhood and the risk of islet autoimmunity and type 1 diabetes (T1D). METHODS: The prospective Finnish Type 1 Diabetes Prediction and Prevention (DIPP)…

Nucleic Acids Res. 2022 Nov 11;50(20):11470-11491. doi: 10.1093/nar/gkac900. ABSTRACT Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA turnover pathway that depends on the endonuclease SMG6. Here, we show that SMG6 is essential for male germ cell differentiation in mice. Germ-cell conditional knockout (cKO) of Smg6 induces extensive…