Clin Chem. 2024 Jun 22:hvae087. doi: 10.1093/clinchem/hvae087. Online ahead of print. ABSTRACT BACKGROUND: Primary prevention is the cornerstone of cardiometabolic health. In the randomized, controlled Special Turku Coronary Risk Factor Intervention Project (STRIP), dietary counseling intervention was given to children from infancy to 20 years of age and a follow-up…
Publications
Publications
Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child
Clin Nutr ESPEN. 2024 Aug;62:22-27. doi: 10.1016/j.clnesp.2024.05.001. Epub 2024 May 11. ABSTRACT BACKGROUND & AIMS: Maternal gluten intake in relation to child’s risk of type 1 diabetes has been studied in few prospective studies considering the diet during pregnancy but none during lactation. Our aim was to study whether gluten,…
The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study
J Endocr Soc. 2024 May 24;8(7):bvae103. doi: 10.1210/jendso/bvae103. eCollection 2024 May 23. ABSTRACT CONTEXT: The 2 peaks of type 1 diabetes incidence occur during early childhood and puberty. OBJECTIVE: We sought to better understand the relationship between puberty, islet autoimmunity, and type 1 diabetes. METHODS: The relationships between puberty, islet…
Change in cognitive performance during seven-year follow-up in midlife is associated with sex, age, and education – The Cardiovascular Risk in Young Finns Study
J Neurol. 2024 Jun 2. doi: 10.1007/s00415-024-12466-2. Online ahead of print. ABSTRACT OBJECTIVE: Sex, age, and education are associated with the level of cognitive performance. We investigated whether these factors modulate the change in cognitive performance in midlife by leveraging the longitudinal data from the Cardiovascular Risk in Young Finns…
Caesarean section and risk of type 1 diabetes
Diabetologia. 2024 May 31. doi: 10.1007/s00125-024-06176-7. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: Delivery by Caesarean section continues to rise globally and has been associated with the risk of developing type 1 diabetes and the rate of progression from pre-symptomatic stage 1 or 2 type 1 diabetes to symptomatic stage 3…
Does the effect of adolescent health behaviours on adult cardiometabolic health differ by socioeconomic background? Protocol for a population-based cohort study
BMJ Open. 2024 May 28;14(5):e078428. doi: 10.1136/bmjopen-2023-078428. ABSTRACT INTRODUCTION: Adolescence is a sensitive period for cardiometabolic health. Yet, it remains unknown if adolescent health behaviours, such as alcohol use, smoking, diet and physical activity, have differential effects across socioeconomic strata. Adopting a life-course perspective and a causal inference framework, we…
Determinants of echocardiographic epicardial adipose tissue in a general middle-aged population – The Cardiovascular Risk in Young Finns Study
Sci Rep. 2024 May 25;14(1):11982. doi: 10.1038/s41598-024-61727-7. ABSTRACT Epicardial adipose tissue (EAT) is the cardiac visceral fat depot proposed to play a role in the etiology of various cardiovascular disease outcomes. Little is known about EAT determinants in a general population. We examined cardiometabolic, dietary, lifestyle and socioeconomic determinants of…
Gut inflammation markers, diet, and risk of islet autoimmunity in Finnish children – a nested case-control study
J Nutr. 2024 May 23:S0022-3166(24)00292-X. doi: 10.1016/j.tjnut.2024.05.015. Online ahead of print. ABSTRACT BACKGROUND: Gut dysbiosis and increased intestinal permeability have been reported to precede type 1 diabetes related autoimmunity. Role of gut inflammation in autoimmunity is not understood. OBJECTIVES: To assess whether gut inflammation markers are associated with risk of…
Physical activity and risk of workplace and commuting injuries: a cohort study
Scand J Work Environ Health. 2024 May 23:4163. doi: 10.5271/sjweh.4163. Online ahead of print. ABSTRACT OBJECTIVE: Leisure-time physical activity (PA) has been hypothesized to reduce the likelihood of occupational injuries, but it is unclear whether this association varies between workplace and commuting injuries. The aim of this study was to…
Personalized Intervention Based on Early Detection of Atherosclerosis: JACC State-of-the-Art Review
J Am Coll Cardiol. 2024 May 28;83(21):2112-2127. doi: 10.1016/j.jacc.2024.02.053. ABSTRACT Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide and challenges the capacity of health care systems globally. Atherosclerosis is the underlying pathophysiological entity in two-thirds of patients with CVD. When considering that atherosclerosis develops over decades,…
