Publications

Circulation. 2024 Nov 6. doi: 10.1161/CIRCULATIONAHA.124.069820. Online ahead of print. ABSTRACT BACKGROUND: Blood pressure (BP)-lowering effects of structured exercise are well-established. Effects of 24-hour movement behaviors captured in free-living settings have received less attention. This cross-sectional study investigated associations between a 24-hour behavior composition comprising 6 parts (sleeping, sedentary behavior,…

Arch Womens Ment Health. 2024 Nov 5. doi: 10.1007/s00737-024-01523-4. Online ahead of print. ABSTRACT PURPOSE: The growing interest in parental cognition calls for research clarifying how cognition interacts with other parenting determinants to shape caregiving behavior. We studied the interplay between executive functioning (EF; cognitive processes that enable goal-directed thinking…

Nat Rev Endocrinol. 2024 Nov 4. doi: 10.1038/s41574-024-01045-0. Online ahead of print. ABSTRACT The goal of the TEDDY (The Environmental Determinants of Diabetes in the Young) study is to elucidate factors leading to the initiation of islet autoimmunity (first primary outcome) and those related to progression to type 1 diabetes…

JAMA Pediatr. 2024 Nov 4. doi: 10.1001/jamapediatrics.2024.4368. Online ahead of print. ABSTRACT IMPORTANCE: Despite its relevance for pediatric blood pressure (BP) screening, the long-term predictive utility and natural progression of pediatric BP classification remain understudied. OBJECTIVE: To evaluate BP tracking from childhood to midadulthood using the American Academy of Pediatrics…

Environ Int. 2024 Oct 22;193:109093. doi: 10.1016/j.envint.2024.109093. Online ahead of print. ABSTRACT OBJECTIVE: Early life microbial exposure influences the composition of gut microbiota. We investigated how early life factors, and the green living environment around infants’ homes, influence the development of gut microbiota during infancy by utilizing data from the…

Acta Paediatr. 2024 Nov 1. doi: 10.1111/apa.17479. Online ahead of print. ABSTRACT AIM: This study aimed to assess the cognitive development of individuals with congenital hypothyroidism. METHODS: Using hospital records, we identified 180 patients with congenital hypothyroidism born between 1980 and 2018 in Turku and Kuopio University Hospital catchment areas.

Biosci Rep. 2024 Oct 30:BSR20240763. doi: 10.1042/BSR20240763. Online ahead of print. ABSTRACT Early-onset pre-eclampsia is believed to arise from defective placentation in the 1st trimester, leading to placental ischaemia/reperfusion (I/R) and oxidative stress. However, our current understanding of the effects of I/R and oxidative stress on trophoblast function is ambiguous…

Scand J Med Sci Sports. 2024 Nov;34(11):e14751. doi: 10.1111/sms.14751. ABSTRACT There is scarcity of studies using device-based measures to examine how relationship and parenthood transitions modify 24-h movement behaviors. This study examined how the composition of 24-h movement behaviors changes during these life transitions. Young adults (n = 170, mean…

Sci Rep. 2024 Oct 26;14(1):25463. doi: 10.1038/s41598-024-75496-w. ABSTRACT Season of birth, viral infections, HLA haplogenotypes and non-HLA variants are implicated in the development of celiac disease and celiac disease autoimmunity, suggesting a combined role of genes and environmental exposures. The aim of the study was to further decipher the biological…

Aging Cell. 2024 Oct 25:e14394. doi: 10.1111/acel.14394. Online ahead of print. ABSTRACT Evidence is accumulating on the connection of early adversities and harsh family environment with epigenetic ageing. We investigated whether early psychosocial resilience is associated with epigenetic ageing in adulthood. We used the population-based Young Finns data (n =…