J Intern Med. 2023 May 4. doi: 10.1111/joim.13648. Online ahead of print. ABSTRACT The etiology of type 1 diabetes (T1D) foreshadows the pancreatic islet beta-cell autoimmune pathogenesis that heralds the clinical onset of T1D. Standardized and harmonized tests of autoantibodies against insulin (IAA), glutamic acid decarboxylase (GADA), islet antigen-2 (IA-2A),…
Publications
Publications
Mother-infant interaction and maternal postnatal psychological distress are associated with negative emotional reactivity among infants and toddlers- A FinnBrain Birth Cohort study
Infant Behav Dev. 2023 Jun 5;72:101843. doi: 10.1016/j.infbeh.2023.101843. Online ahead of print. ABSTRACT Studies have reported mixed findings regarding the effects of mother-infant interaction and maternal distress on children’s negative emotional reactivity. In the current study (N = 134 and 107), we examined the effects of maternal Emotional Availability (sensitivity,…
Comorbidity in congenital hypothyroidism – A nationwide population-based cohort study
J Clin Endocrinol Metab. 2023 Jun 6:dgad334. doi: 10.1210/clinem/dgad334. Online ahead of print. ABSTRACT CONTEXT: Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties. OBJECTIVE: The aim of this nationwide population-based register study was to investigate the incidence of…
Dietary patterns from youth to adulthood and cognitive function in midlife: The cardiovascular risk in Young Finns Study
Nutrition. 2023 Aug;112:112063. doi: 10.1016/j.nut.2023.112063. Epub 2023 Apr 27. ABSTRACT OBJECTIVES: Diet plays an important role in cognitive health, but the long-term association of diet early in life with cognitive function in adulthood has not, to our knowledge, been rigorously studied. The aim of this study was to examine the…
Prediction of pre-diabetes and type 2 diabetes nine years postpartum using serum metabolome in pregnant women with gestational diabetes requiring pharmacological treatment
J Diabetes Complications. 2023 Jul;37(7):108513. doi: 10.1016/j.jdiacomp.2023.108513. Epub 2023 May 26. ABSTRACT AIMS: We examined the association between serum metabolome in women with pharmacologically treated gestational diabetes (GDM) and measures of glucose metabolism 9 years postpartum. METHODS: Serum targeted metabolome, adiponectin, inflammatory markers, and insulin-like growth factor-binding protein-1 phosphoisoforms were…
Hair cortisol, cortisone and DHEA concentrations and the composition of microbiota in toddlers
Psychoneuroendocrinology. 2023 Aug;154:106309. doi: 10.1016/j.psyneuen.2023.106309. Epub 2023 May 25. ABSTRACT Animal research suggests that the gut microbiota and the HPA axis communicate in a bidirectional manner. However, human data, especially on early childhood, remain limited. In this exploratory design, we investigated the connections between long-term HPA axis functioning, measured as…
Childhood trauma and fear of childbirth: findings from a birth cohort study
Arch Womens Ment Health. 2023 May 27. doi: 10.1007/s00737-023-01328-x. Online ahead of print. ABSTRACT The aim of this study is to investigate if experiencing childhood trauma (emotional abuse, emotional neglect, physical abuse, physical neglect, or sexual abuse) or a greater total burden of childhood trauma increase the risk of fear…
Author Correction: The power of genetic diversity in genome-wide association studies of lipids
Nature. 2023 Jun;618(7965):E19-E20. doi: 10.1038/s41586-023-06194-2. NO ABSTRACT PMID:37237109 | DOI:10.1038/s41586-023-06194-2…
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis
Epigenetics. 2023 Dec;18(1):2211361. doi: 10.1080/15592294.2023.2211361. ABSTRACT BACKGROUND: Dietary intake of antioxidants such as vitamins C and E protect against oxidative stress, and may also be associated with altered DNA methylation patterns. METHODS: We meta-analysed epigenome-wide association study (EWAS) results from 11,866 participants across eight population-based cohorts to evaluate the association…
Investigating the role of relationship satisfaction and paternal psychological distress during pregnancy on offspring health in early life
BJPsych Open. 2023 May 25;9(3):e100. doi: 10.1192/bjo.2023.59. ABSTRACT BACKGROUND: The research on the role of father in the foetal programming of health and behaviour has received increasing attention. However, the influences of paternal depressive symptoms and couple relationship satisfaction during pregnancy – potentially mediated via maternal well-being – on the…
