Robust inference and widespread genetic correlates from a large-scale genetic association study of human personality

bioRxiv [Preprint]. 2025 May 19:2025.05.16.648988. doi: 10.1101/2025.05.16.648988. ABSTRACT Personality traits describe stable differences in how individuals think, feel, and behave and how they interact with and experience their social and physical environments. We assemble data from 46 cohorts including 611K-1.14M participants with European-like and African-like genomes for genome-wide association studies…

Effect of gestational anemia on breastfeeding- a prospective follow-up -study

BMC Pregnancy Childbirth. 2025 Jun 4;25(1):653. doi: 10.1186/s12884-025-07775-x. ABSTRACT BACKGROUND: Gestational anemia is a common pregnancy complication that affects approximately 40% of pregnant women globally. The health benefits of breastfeeding are widely acknowledged for both mothers and infants, and recognizing the factors that affect the duration and quality (exclusive /…

Association of leisure time physical activity with gut microbiota composition in early adulthood

Sci Rep. 2025 Jun 4;15(1):19697. doi: 10.1038/s41598-025-02287-2. ABSTRACT Physical activity is associated with compositional changes in gut microbiota. Studies applying data from general populations exhibiting varying physical activity levels are scarce. This study investigated the associations between leisure time physical activity and gut microbiota composition in a general population of…

Continuity of active commuting to school across two generations: the Cardiovascular Risk in Young Finns Study

Eur J Public Health. 2025 Jun 3:ckaf084. doi: 10.1093/eurpub/ckaf084. Online ahead of print. ABSTRACT Active commuting to school (ACS) may markedly contribute to overall physical activity (PA) among youth, but ACS levels have declined in recent decades. Parents significantly influence their children’s PA and commuting behaviours, and lifestyle habits are…

Cardiometabolic determinants of aortic and carotid intima-media thickness in adolescence

Atherosclerosis. 2025 May 21;406:120218. doi: 10.1016/j.atherosclerosis.2025.120218. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Comprehensive longitudinal data in healthy populations on cardiometabolic determinants of arterial intima-media thickness (IMT), especially aortic IMT, in adolescence are lacking. We aimed to examine in detail how cardiometabolic risk factors associate with aortic and carotid…

Polygenic risk for schizophrenia predicting Big Five personality traits in individuals without non-affective psychosis

Schizophr Res. 2025 May 23;281:229-236. doi: 10.1016/j.schres.2025.05.017. Online ahead of print. ABSTRACT BACKGROUND: A high genetic risk for schizophrenia, in complex interplay with environmental factors, has been suggested to explain population-level variation in personality traits among individuals who do not develop schizophrenia-spectrum disorders. We investigated, first, whether polygenic risk for…

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