Publications

Elife. 2026 Feb 2;12:RP89068. doi: 10.7554/eLife.89068. ABSTRACT Polymorphisms in genes in the human leukocyte antigen (HLA) class II region comprise the most important inherited risk factors for many autoimmune diseases, including type 1 diabetes (T1D) and celiac disease (CD): both diseases are positively associated with the HLA-DR3 haplotype (DRB1*03:01-DQA1*05:01-DQB1*02:01). Studies…

Dev Cogn Neurosci. 2026 Jan 9;78:101672. doi: 10.1016/j.dcn.2026.101672. Online ahead of print. ABSTRACT Early executive function (EF) development is crucial for later cognitive and socioemotional outcomes, yet the role of environmental unpredictability, particularly in patterns of maternal sensory signals, remains underexplored. In this longitudinal study, we investigated the associations between…

EBioMedicine. 2026 Jan 30;124:106144. doi: 10.1016/j.ebiom.2026.106144. Online ahead of print. ABSTRACT BACKGROUND: Cholesterol is a main contributor to coronary artery disease (CAD). Although the genetic basis of blood cholesterol concentration is well studied, there is currently a lack of studies investigating the genetics of its precursors from de novo biosynthesis.

Am J Perinatol. 2026 Jan 29. doi: 10.1055/a-2788-2020. Online ahead of print. ABSTRACT This study aimed to evaluate the efficacy and safety of continuous intravenous (IV) glucagon infusion in the management of neonatal hypoglycemia in infants of diabetic mothers (IDMs).This retrospective case-control study included IDMs treated for hypoglycemia at Turku…

Am J Epidemiol. 2026 Jan 23:kwag016. doi: 10.1093/aje/kwag016. Online ahead of print. ABSTRACT We aimed to determine if thyroid autoimmunity is associated with a child’s risk for subsequent development of islet or celiac autoantibodies. Children at high genetic risk of type 1 diabetes were followed for thyroid autoimmunity (thyroid peroxidase…

Commun Biol. 2026 Jan 23. doi: 10.1038/s42003-025-09488-5. Online ahead of print. ABSTRACT Perinatal period is a critical time for brain development and premature-born children have an elevated likelihood for neurodevelopmental conditions. While strong associations of structural magnetic resonance imaging with preterm birth and post-menstrual age (PMA) have been reported, results…

Pediatr Res. 2026 Jan 15. doi: 10.1038/s41390-025-04726-2. Online ahead of print. ABSTRACT BACKGROUND: Elevated pre-pregnancy body mass index (BMI) and perinatal depressive symptoms have been linked to neonatal alterations in brain structure and function. This study examined associations between neonatal functional brain dynamics, maternal BMI, and perinatal depressive symptoms measured…

Pediatrics. 2026 Jan 15:e2025071353. doi: 10.1542/peds.2025-071353. Online ahead of print. ABSTRACT OBJECTIVE: Cardiovascular health promotion in adulthood is crucial for early prevention of cognitive decline, but prior data on the role of promotion starting from infancy are scarce. We studied the associations between cardiovascular risk factors from infancy to young…

BMC Psychiatry. 2026 Jan 12. doi: 10.1186/s12888-026-07775-x. Online ahead of print. ABSTRACT INTRODUCTION: Schizophrenia is characterized by weaker test-measured cognitive performance, which is partially explained by disease-related secondary factors (after the onset of the disorder) such as side effects of antipsychotics, stigma, or sedentary behavior. We examined whether polygenic risk…

Scand J Public Health. 2026 Jan 11:14034948251395569. doi: 10.1177/14034948251395569. Online ahead of print. ABSTRACT AIMS: Leisure-time physical activity (LTPA) is known to be hereditary for two generations, but its transmission beyond that is less studied. This study examined LTPA aggregation in three-generation families. METHODS: Data on self-reported LTPA were extracted…