Publications

J Allergy Clin Immunol. 2026 Feb 20:S0091-6749(26)00093-X. doi: 10.1016/j.jaci.2026.02.012. Online ahead of print. ABSTRACT BACKGROUND: Food allergies (FA) arise from a complex interplay between an individual’s genetic predisposition and environmental factors and their prevalence is increasing. Genome-wide association studies (GWAS) to date have been hindered by small sample sizes and…

Sci Total Environ. 2026 Feb 19;1020:181552. doi: 10.1016/j.scitotenv.2026.181552. Online ahead of print. ABSTRACT INTRODUCTION: Whether early-life exposure to persistent organic pollutants (POPs) associates with adult cognitive function is unknown. We examined the association of childhood serum POPs levels with cognitive function in midlife. METHODS: This was a prospective cohort study…

Epigenomics. 2026 Feb 17:1-11. doi: 10.1080/17501911.2026.2630841. Online ahead of print. ABSTRACT AIM: Tobacco smoking induces persistent DNA methylation (DNAm) changes in blood that can serve as long-term biomarkers for smoking exposure. We aimed to develop and validate a DNAm classifier of smoking status using Illumina EPIC array data. METHODS: We…

Int J Cardiol. 2026 Feb 2:134216. doi: 10.1016/j.ijcard.2026.134216. Online ahead of print. ABSTRACT BACKGROUND: Neighbourhood socioeconomic disadvantage correlates with cardiovascular disease risk. However, its relationship with subclinical atherosclerosis from childhood to midlife is not well-defined. We examined whether cumulative neighbourhood disadvantage is associated with carotid artery plaques, a measure of…

Compr Psychoneuroendocrinol. 2025 Nov 4;24:100325. doi: 10.1016/j.cpnec.2025.100325. eCollection 2025 Nov. ABSTRACT OBJECTIVES: Retirement is a significant life event involving removal of work stress and changes in other psychological factors. These changes may induce physiological responses in the body, such as changes in levels of the stress hormone cortisol, but no…

Elife. 2026 Feb 2;12:RP89068. doi: 10.7554/eLife.89068. ABSTRACT Polymorphisms in genes in the human leukocyte antigen (HLA) class II region comprise the most important inherited risk factors for many autoimmune diseases, including type 1 diabetes (T1D) and celiac disease (CD): both diseases are positively associated with the HLA-DR3 haplotype (DRB1*03:01-DQA1*05:01-DQB1*02:01). Studies…

Dev Cogn Neurosci. 2026 Jan 9;78:101672. doi: 10.1016/j.dcn.2026.101672. Online ahead of print. ABSTRACT Early executive function (EF) development is crucial for later cognitive and socioemotional outcomes, yet the role of environmental unpredictability, particularly in patterns of maternal sensory signals, remains underexplored. In this longitudinal study, we investigated the associations between…

EBioMedicine. 2026 Jan 30;124:106144. doi: 10.1016/j.ebiom.2026.106144. Online ahead of print. ABSTRACT BACKGROUND: Cholesterol is a main contributor to coronary artery disease (CAD). Although the genetic basis of blood cholesterol concentration is well studied, there is currently a lack of studies investigating the genetics of its precursors from de novo biosynthesis.

Am J Perinatol. 2026 Jan 29. doi: 10.1055/a-2788-2020. Online ahead of print. ABSTRACT This study aimed to evaluate the efficacy and safety of continuous intravenous (IV) glucagon infusion in the management of neonatal hypoglycemia in infants of diabetic mothers (IDMs).This retrospective case-control study included IDMs treated for hypoglycemia at Turku…

Am J Epidemiol. 2026 Jan 23:kwag016. doi: 10.1093/aje/kwag016. Online ahead of print. ABSTRACT We aimed to determine if thyroid autoimmunity is associated with a child’s risk for subsequent development of islet or celiac autoantibodies. Children at high genetic risk of type 1 diabetes were followed for thyroid autoimmunity (thyroid peroxidase…