Diabetes Care. 2023 May 1;46(5):1014-1018. doi: 10.2337/dc22-1359. ABSTRACT OBJECTIVE: To examine whether iron intake and genetically determined iron overload interact in predisposing to the development of childhood islet autoimmunity (IA) and type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS: In The Environmental Determinants of Diabetes in the Young (TEDDY) study,…
Publications
Publications
Senior Health Clinic for 75-year-old home-dwelling Finns – study design, clinic protocol and non-response analysis
BMC Health Serv Res. 2023 Mar 2;23(1):210. doi: 10.1186/s12913-023-09199-9. ABSTRACT BACKGROUND: In the Finnish policy on older people preventive activities, which maintain functional capacity and independent living, are emphasized. The Turku Senior Health Clinic, aimed at maintaining independent coping of all home-dwelling 75-year-old citizens in the city of Turku, was…
Association of Sit-to-Stand Capacity and Free-Living Performance Using Thigh-Worn Accelerometers among 60-90-Year-Old Adults
Med Sci Sports Exerc. 2023 Apr 3. doi: 10.1249/MSS.0000000000003178. Online ahead of print. ABSTRACT PURPOSE: Five times sit-to-stand (STS) test is commonly used as a clinical assessment of lower-extremity functional ability, but its association with free-living performance has not been studied. Therefore, we investigated the association between laboratory-based STS capacity…
Higher attention bias for fear at 8 months of age is associated with better socioemotional competencies during toddlerhood
Infant Behav Dev. 2023 May;71:101838. doi: 10.1016/j.infbeh.2023.101838. Epub 2023 Mar 28. ABSTRACT BACKGROUND: In previous studies, an attention bias for signals of fear and threat has been related to socioemotional problems, such as anxiety symptoms, and socioemotional competencies, such as altruistic behaviors in children, adolescents and adults. However, previous studies…
Exposure to Phthalates in European Children, Adolescents and Adults since 2005: A Harmonized Approach Based on Existing HBM Data in the HBM4EU Initiative
Toxics. 2023 Mar 4;11(3):241. doi: 10.3390/toxics11030241. ABSTRACT Phthalates are mainly used as plasticizers and are associated inter alia with adverse effects on reproductive functions. While more and more national programs in Europe have started monitoring internal exposure to phthalates and its substitute 1,2-Cyclohexanedicarboxylic acid (DINCH), the comparability of results from…
Pre- and postnatal maternal depressive symptoms associate with white matter integrity in 5-year-olds in sex-specific manner
Biol Psychiatry. 2023 May 21:S0006-3223(23)01301-X. doi: 10.1016/j.biopsych.2023.05.014. Online ahead of print. ABSTRACT BACKGROUND: Pre- and postnatal maternal psychological distress predicts various detrimental consequences on social, behavioural, and cognitive development of the offspring and especially in girls. Maturation of white matter (WM) continues from prenatal development into adulthood and is thus…
Longitudinal consumption of fruits and vegetables and risk of asthma by 5 years of age
Pediatr Allergy Immunol. 2023 Mar;34(3):e13932. doi: 10.1111/pai.13932. ABSTRACT BACKGROUND: Fruit and vegetable consumption has been linked to a decreased risk of asthma, but prospective evidence on longitudinal consumption in childhood is scarce. We aimed to investigate the association between fruit and vegetable consumption in childhood and the risk of asthma…
Associations of active commuting to school in childhood and physical activity in adulthood
Sci Rep. 2023 May 11;13(1):7642. doi: 10.1038/s41598-023-33518-z. ABSTRACT This study examined whether active commuting to school in childhood and adolescence predicted active commuting to work and overall physical activity (PA) in adulthood. Participants from the Young Finns Study (N = 2436) were aged 9-18 years in 1980 and followed up…
Workplace Psychosocial Resources and Risk of Sleep Disturbances Among Employees
JAMA Netw Open. 2023 May 1;6(5):e2312514. doi: 10.1001/jamanetworkopen.2023.12514. ABSTRACT IMPORTANCE: Workplace psychosocial resources naturally tend to cluster in some work teams. To inform work-related sleep health promotion interventions, it is important to determine the associations between clustering of workplace resources and sleep disturbances when some resources are high while others…
Gene Set Based Integrated Methylome and Transcriptome Analysis Reveals Potential Molecular Mechanisms Linking Cigarette Smoking and Related Diseases
OMICS. 2023 May;27(5):193-204. doi: 10.1089/omi.2023.0028. Epub 2023 May 5. ABSTRACT Advanced integrative analysis of DNA methylation and transcriptomics data may provide deeper insights into smoke-induced epigenetic alterations, their effects on gene expression and related biological processes, linking cigarette smoking and related diseases. We hypothesize that accumulation of DNA methylation changes…
