Intravenous Glucagon Infusion in the Management of Hypoglycemia in Infants of Diabetic Mothers

Am J Perinatol. 2026 Jan 29. doi: 10.1055/a-2788-2020. Online ahead of print. ABSTRACT This study aimed to evaluate the efficacy and safety of continuous intravenous (IV) glucagon infusion in the management of neonatal hypoglycemia in infants of diabetic mothers (IDMs).This retrospective case-control study included IDMs treated for hypoglycemia at Turku…

Read More

Thyroid autoimmunity and the subsequent development of islet and celiac autoimmunity in the TEDDY study

Am J Epidemiol. 2026 Jan 23:kwag016. doi: 10.1093/aje/kwag016. Online ahead of print. ABSTRACT We aimed to determine if thyroid autoimmunity is associated with a child’s risk for subsequent development of islet or celiac autoantibodies. Children at high genetic risk of type 1 diabetes were followed for thyroid autoimmunity (thyroid peroxidase…

Read More

Aperiodic parameters of the fMRI power spectrum associate with preterm birth and neonatal age

Commun Biol. 2026 Jan 23. doi: 10.1038/s42003-025-09488-5. Online ahead of print. ABSTRACT Perinatal period is a critical time for brain development and premature-born children have an elevated likelihood for neurodevelopmental conditions. While strong associations of structural magnetic resonance imaging with preterm birth and post-menstrual age (PMA) have been reported, results…

Read More

Investigating the influence of maternal prenatal BMI and perinatal depressive symptoms on neonatal brain network dynamics

Pediatr Res. 2026 Jan 15. doi: 10.1038/s41390-025-04726-2. Online ahead of print. ABSTRACT BACKGROUND: Elevated pre-pregnancy body mass index (BMI) and perinatal depressive symptoms have been linked to neonatal alterations in brain structure and function. This study examined associations between neonatal functional brain dynamics, maternal BMI, and perinatal depressive symptoms measured…

Read More

Cardiovascular Risk Factors From Early Childhood and Cognitive Function in Young Adulthood

Pediatrics. 2026 Jan 15:e2025071353. doi: 10.1542/peds.2025-071353. Online ahead of print. ABSTRACT OBJECTIVE: Cardiovascular health promotion in adulthood is crucial for early prevention of cognitive decline, but prior data on the role of promotion starting from infancy are scarce. We studied the associations between cardiovascular risk factors from infancy to young…

Read More

Polygenic risk for schizophrenia predicting test-measured and self-reported cognitive performance in individuals without psychosis

BMC Psychiatry. 2026 Jan 12. doi: 10.1186/s12888-026-07775-x. Online ahead of print. ABSTRACT INTRODUCTION: Schizophrenia is characterized by weaker test-measured cognitive performance, which is partially explained by disease-related secondary factors (after the onset of the disorder) such as side effects of antipsychotics, stigma, or sedentary behavior. We examined whether polygenic risk…

Read More

Familial aggregation of leisure-time physical activity across three generations: The Cardiovascular Risk in Young Finns Study

Scand J Public Health. 2026 Jan 11:14034948251395569. doi: 10.1177/14034948251395569. Online ahead of print. ABSTRACT AIMS: Leisure-time physical activity (LTPA) is known to be hereditary for two generations, but its transmission beyond that is less studied. This study examined LTPA aggregation in three-generation families. METHODS: Data on self-reported LTPA were extracted…

Read More

A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations

HGG Adv. 2026 Jan 10:100566. doi: 10.1016/j.xhgg.2026.100566. Online ahead of print. ABSTRACT Gene-environment interactions may enhance our understanding of blood pressure (BP) biology. We conducted a meta-analysis of multi-population genome-wide association studies of BP traits accounting for gene-depressive symptomatology (DEPR) interactions. Our study included 564,680 adults from 67 cohorts and…

Read More

Genome-wide DNA methylation patterns for indicators of liver steatosis: a longitudinal multiomic study

Clin Epigenetics. 2026 Jan 3. doi: 10.1186/s13148-025-02037-1. Online ahead of print. ABSTRACT BACKGROUND: To identify blood DNA methylation profiles related to liver steatosis, we performed an EWAS on the presence of ultrasonically-identified liver steatosis in the Young Finns Study (YFS) participants (n = 1529, 33-50y.), and on liver enzyme levels…

Read More
utu logo vsshp logo