Publications

MethodsX. 2024 Jun 1;12:102789. doi: 10.1016/j.mex.2024.102789. eCollection 2024 Jun. ABSTRACT Large multi-site studies that combine magnetic resonance imaging (MRI) data across research sites present exceptional opportunities to advance neuroscience research. However, scanner or site variability and non-standardised image acquisition protocols, data processing and analysis pipelines can adversely affect the reliability…

Cell Rep. 2024 Jul 3;43(7):114430. doi: 10.1016/j.celrep.2024.114430. Online ahead of print. ABSTRACT Cancer cells undergo major epigenetic alterations and transcriptomic changes, including ectopic expression of tissue- and cell-type-specific genes. Here, we show that the germline-specific RNA helicase DDX4 forms germ-granule-like cytoplasmic ribonucleoprotein granules in various human tumors, but not in…

Front Endocrinol (Lausanne). 2024 Jun 10;15:1435877. doi: 10.3389/fendo.2024.1435877. eCollection 2024. NO ABSTRACT PMID:38915895 | PMC:PMC11194432 | DOI:10.3389/fendo.2024.1435877…

JAMA Netw Open. 2024 Jun 3;7(6):e2418148. doi: 10.1001/jamanetworkopen.2024.18148. ABSTRACT IMPORTANCE: Recent evidence suggests that childhood levels of serum lipids, blood pressure, body mass index (BMI), and smoking contribute to adult risk of cardiovascular disease (CVD). Evidence is lacking on whether this is independent of adult risk levels. OBJECTIVE: To quantify…

Clin Chem. 2024 Jun 22:hvae087. doi: 10.1093/clinchem/hvae087. Online ahead of print. ABSTRACT BACKGROUND: Primary prevention is the cornerstone of cardiometabolic health. In the randomized, controlled Special Turku Coronary Risk Factor Intervention Project (STRIP), dietary counseling intervention was given to children from infancy to 20 years of age and a follow-up…

Clin Nutr ESPEN. 2024 Aug;62:22-27. doi: 10.1016/j.clnesp.2024.05.001. Epub 2024 May 11. ABSTRACT BACKGROUND & AIMS: Maternal gluten intake in relation to child’s risk of type 1 diabetes has been studied in few prospective studies considering the diet during pregnancy but none during lactation. Our aim was to study whether gluten,…

J Endocr Soc. 2024 May 24;8(7):bvae103. doi: 10.1210/jendso/bvae103. eCollection 2024 May 23. ABSTRACT CONTEXT: The 2 peaks of type 1 diabetes incidence occur during early childhood and puberty. OBJECTIVE: We sought to better understand the relationship between puberty, islet autoimmunity, and type 1 diabetes. METHODS: The relationships between puberty, islet…

J Neurol. 2024 Jun 2. doi: 10.1007/s00415-024-12466-2. Online ahead of print. ABSTRACT OBJECTIVE: Sex, age, and education are associated with the level of cognitive performance. We investigated whether these factors modulate the change in cognitive performance in midlife by leveraging the longitudinal data from the Cardiovascular Risk in Young Finns…

Diabetologia. 2024 May 31. doi: 10.1007/s00125-024-06176-7. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: Delivery by Caesarean section continues to rise globally and has been associated with the risk of developing type 1 diabetes and the rate of progression from pre-symptomatic stage 1 or 2 type 1 diabetes to symptomatic stage 3…

BMJ Open. 2024 May 28;14(5):e078428. doi: 10.1136/bmjopen-2023-078428. ABSTRACT INTRODUCTION: Adolescence is a sensitive period for cardiometabolic health. Yet, it remains unknown if adolescent health behaviours, such as alcohol use, smoking, diet and physical activity, have differential effects across socioeconomic strata. Adopting a life-course perspective and a causal inference framework, we…