Publications

Sci Rep. 2024 May 25;14(1):11982. doi: 10.1038/s41598-024-61727-7. ABSTRACT Epicardial adipose tissue (EAT) is the cardiac visceral fat depot proposed to play a role in the etiology of various cardiovascular disease outcomes. Little is known about EAT determinants in a general population. We examined cardiometabolic, dietary, lifestyle and socioeconomic determinants of…

J Nutr. 2024 May 23:S0022-3166(24)00292-X. doi: 10.1016/j.tjnut.2024.05.015. Online ahead of print. ABSTRACT BACKGROUND: Gut dysbiosis and increased intestinal permeability have been reported to precede type 1 diabetes related autoimmunity. Role of gut inflammation in autoimmunity is not understood. OBJECTIVES: To assess whether gut inflammation markers are associated with risk of…

Scand J Work Environ Health. 2024 May 23:4163. doi: 10.5271/sjweh.4163. Online ahead of print. ABSTRACT OBJECTIVE: Leisure-time physical activity (PA) has been hypothesized to reduce the likelihood of occupational injuries, but it is unclear whether this association varies between workplace and commuting injuries. The aim of this study was to…

J Am Coll Cardiol. 2024 May 28;83(21):2112-2127. doi: 10.1016/j.jacc.2024.02.053. ABSTRACT Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide and challenges the capacity of health care systems globally. Atherosclerosis is the underlying pathophysiological entity in two-thirds of patients with CVD. When considering that atherosclerosis develops over decades,…

Genome Biol. 2024 May 21;25(1):129. doi: 10.1186/s13059-024-03276-w. NO ABSTRACT PMID:38773652 | DOI:10.1186/s13059-024-03276-w…

Front Psychiatry. 2024 Apr 25;15:1345159. doi: 10.3389/fpsyt.2024.1345159. eCollection 2024. ABSTRACT BACKGROUND: Studies have shown that cardiovascular health (CVH) is related to depression. We aimed to identify gene networks jointly associated with depressive symptoms and cardiovascular health metrics using the whole blood transcriptome. MATERIALS AND METHODS: We analyzed human blood transcriptomic…

Nat Commun. 2024 May 7;15(1):3810. doi: 10.1038/s41467-024-47918-w. ABSTRACT Previous studies have revealed heterogeneity in the progression to clinical type 1 diabetes in children who develop islet-specific antibodies either to insulin (IAA) or glutamic acid decarboxylase (GADA) as the first autoantibodies. Here, we test the hypothesis that children who later develop…

J Phys Act Health. 2024 May 2:1-9. doi: 10.1123/jpah.2023-0558. Online ahead of print. ABSTRACT BACKGROUND: Retirement transition has been shown to associate with changes in physical activity (PA) and self-rated health (SRH), but their interrelationship is less studied. The aim was to investigate changes in accelerometer-measured total PA, moderate to…

Biosci Rep. 2024 May 3:BSR20240562. doi: 10.1042/BSR20240562. Online ahead of print. ABSTRACT Pre-eclampsia (PE) is a hypertensive disorder of pregnancy which is associated with increased risk of neurodevelopmental disorders in exposed offspring. The pathophysiological mechanisms mediating this relationship are currently unknown, and one potential candidate is the anti-angiogenic factor soluble…

BMC Med Inform Decis Mak. 2024 May 2;24(1):116. doi: 10.1186/s12911-024-02521-3. ABSTRACT BACKGROUND: Machine learning (ML) classifiers are increasingly used for predicting cardiovascular disease (CVD) and related risk factors using omics data, although these outcomes often exhibit categorical nature and class imbalances. However, little is known about which ML classifier, omics…