Association of neighbourhood and individual-level socioeconomic disadvantage in childhood and adulthood with cognitive function in mid-adulthood: Cardiovascular Risk in Young Finns Study

Am J Epidemiol. 2025 Mar 7:kwaf032. doi: 10.1093/aje/kwaf032. Online ahead of print. ABSTRACT Socioeconomic disadvantage at individual level is associated with poor cognitive outcomes but the link of neighbourhood disadvantage with cognitive function is unclear. We used data from Young Finns Study, a population-based cohort, to examine the associations of…

The association of childhood HDL cholesterol with atherosclerotic CVD events in adults: findings from the International Childhood Cardiovascular Cohort Consortium

Eur J Prev Cardiol. 2025 Mar 5:zwaf117. doi: 10.1093/eurjpc/zwaf117. Online ahead of print. ABSTRACT AIMS: The role of adult HDL-C in atherosclerotic cardiovascular disease (ASCVD) faces challenges from Mendelian randomisations and drug trials. However, the association between childhood HDL-C and its changes and adult ASCVD remains undefined. This study aimed…

A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations

Res Sq [Preprint]. 2025 Feb 17:rs.3.rs-6025759. doi: 10.21203/rs.3.rs-6025759/v1. ABSTRACT Background Gene-environment interactions may enhance our understanding of hypertension. Our previous study highlighted the importance of considering psychosocial factors in gene discovery for blood pressure (BP) but was limited in statistical power and population diversity. To address these challenges, we conducted…

Associations of 24-h Movement Behaviors With Incidence of Cardiovascular Risk Factors: The Finnish Retirement and Aging Study

Scand J Med Sci Sports. 2025 Feb;35(2):e70030. doi: 10.1111/sms.70030. ABSTRACT Low physical activity, high sedentary time (SED), and inadequate sleep increase cardiovascular disease risk, but the codependency between these 24-h movement behaviors has often been neglected. This study examined associations between 24-h movement behaviors and incidence of cardiovascular risk factors.

From Parents to Children: The Intergenerational Transference of Parents’ Sport Club Participation From Childhood to Adolescence: The 40-Year Young Finns Study

J Phys Act Health. 2025 Feb 19:1-9. doi: 10.1123/jpah.2024-0368. Online ahead of print. ABSTRACT BACKGROUND: Physical activity has been shown to transfer across generations, but more information is needed regarding the transference of different physical activity modes. This study examined (1) whether parents’ sport club participation at the ages 9-18…

Sociodemographic and work-related determinants of self-rated health trajectories: a collaborative meta-analysis of cohort studies from Europe and the US

Sci Rep. 2025 Feb 13;15(1):5394. doi: 10.1038/s41598-025-89947-5. ABSTRACT Self-rated health is a major indicator of an individual’s overall health status, but its development during midlife to old age, as well as influence of sociodemographic and work-related factors on it, are poorly understood. We used longitudinal individual-level data to examine trajectories…

Associations between maternal pre-pregnancy BMI and mean diffusivity of the hippocampus and amygdala in infants

Int J Obes (Lond). 2025 Feb 11. doi: 10.1038/s41366-025-01730-8. Online ahead of print. ABSTRACT BACKGROUND: Maternal pre-pregnancy obesity may negatively affect offspring outcomes, including neurodevelopment. This study examined the relationship between maternal pre-pregnancy body mass index (MBMI) and the microstructure of the hippocampus and amygdala in neonates. METHODS: Diffusion tensor…

Continuous glucose monitor metrics from five studies identify participants at risk for type 1 diabetes development

Diabetologia. 2025 Feb 11. doi: 10.1007/s00125-025-06362-1. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: We aimed to assess whether continuous glucose monitor (CGM) metrics can accurately predict stage 3 type 1 diabetes diagnosis in those with islet autoantibodies (AAb). METHODS: Baseline CGM data were collected from participants with ≥1 positive AAb type…

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