J Clin Endocrinol Metab. 2024 Dec 11:dgae865. doi: 10.1210/clinem/dgae865. Online ahead of print. ABSTRACT CONTEXT: Exogenous insulin is reported to have both vasodilatory and vasoconstrictive effects on the microvasculature. Little is known about the associations of long-term endogenous insulin exposure with microvasculature. OBJECTIVE: To test the hypothesis that long-term exposure…
Publications
Publications
Understanding Resilience in Parents: Longitudinal Examination of Trait Resilience, Stressful Life Events, and Psychological Distress Symptoms-Insights From the FinnBrain Study
Stress Health. 2024 Dec 2:e3516. doi: 10.1002/smi.3516. Online ahead of print. ABSTRACT The study aimed to investigate the persistence or changes in trait resilience of parents over a 6-year period and its association with stressful life events (SLEs). Furthermore, we explored the potential protective effect of trait resilience against exposure…
Efficient Search Algorithms for Identifying Synergistic Associations in High-Dimensional Datasets
Entropy (Basel). 2024 Nov 11;26(11):968. doi: 10.3390/e26110968. ABSTRACT In recent years, there has been a notably increased interest in the study of multivariate interactions and emergent higher-order dependencies. This is particularly evident in the context of identifying synergistic sets, which are defined as combinations of elements whose joint interactions result…
Low-Density Lipoprotein Cholesterol Level Distributions Across Different Ages: Implications for Screening Children for Severe and Familial Hypercholesterolemia
Circulation. 2024 Nov 19;150(21):1741-1744. doi: 10.1161/CIRCULATIONAHA.124.069792. Epub 2024 Nov 18. NO ABSTRACT PMID:39556651 | DOI:10.1161/CIRCULATIONAHA.124.069792…
Associations between Leisure and Work Time Activity Behavior and 24 H Ambulatory Blood Pressure among Aging Workers
Med Sci Sports Exerc. 2024 Nov 6. doi: 10.1249/MSS.0000000000003594. Online ahead of print. ABSTRACT Purpose: The associations between work time, leisure-time, and non-workday physical activity (PA) and sedentary behavior (SED) and 24 h ambulatory blood pressure (BP) are not well known. Therefore, the aim of this study was to evaluate…
Sex-specific associations between maternal prenatal inflammation and offspring cortical morphology in youth: A harmonised study across four birth cohorts
Brain Behav Immun. 2024 Nov 4:S0889-1591(24)00692-5. doi: 10.1016/j.bbi.2024.11.010. Online ahead of print. ABSTRACT Maternal immune activation (MIA) during pregnancy is implicated in offspring psychiatric disorders. However, it is unknown to what extent MIA affects neurodevelopment, particularly cerebrocortical anatomy, in the general population, and whether effects differ by sex. The current…
Device-Measured 24-Hour Movement Behaviors and Blood Pressure: A 6-Part Compositional Individual Participant Data Analysis in the ProPASS Consortium
Circulation. 2024 Nov 6. doi: 10.1161/CIRCULATIONAHA.124.069820. Online ahead of print. ABSTRACT BACKGROUND: Blood pressure (BP)-lowering effects of structured exercise are well-established. Effects of 24-hour movement behaviors captured in free-living settings have received less attention. This cross-sectional study investigated associations between a 24-hour behavior composition comprising 6 parts (sleeping, sedentary behavior,…
Maternal alexithymia and caregiving behavior: the role of executive functioning – A FinnBrain Birth Cohort study
Arch Womens Ment Health. 2024 Nov 5. doi: 10.1007/s00737-024-01523-4. Online ahead of print. ABSTRACT PURPOSE: The growing interest in parental cognition calls for research clarifying how cognition interacts with other parenting determinants to shape caregiving behavior. We studied the interplay between executive functioning (EF; cognitive processes that enable goal-directed thinking…
Looking back at the TEDDY study: lessons and future directions
Nat Rev Endocrinol. 2024 Nov 4. doi: 10.1038/s41574-024-01045-0. Online ahead of print. ABSTRACT The goal of the TEDDY (The Environmental Determinants of Diabetes in the Young) study is to elucidate factors leading to the initiation of islet autoimmunity (first primary outcome) and those related to progression to type 1 diabetes…
Tracking and Transition Probability of Blood Pressure From Childhood to Midadulthood
JAMA Pediatr. 2024 Nov 4. doi: 10.1001/jamapediatrics.2024.4368. Online ahead of print. ABSTRACT IMPORTANCE: Despite its relevance for pediatric blood pressure (BP) screening, the long-term predictive utility and natural progression of pediatric BP classification remain understudied. OBJECTIVE: To evaluate BP tracking from childhood to midadulthood using the American Academy of Pediatrics…
