Int J Epidemiol. 2025 Feb 16;54(2):dyaf026. doi: 10.1093/ije/dyaf026. ABSTRACT BACKGROUND: This is the first large-scale longitudinal study of children that describes the temporal trajectories of an extensive collection of metabolic measures that are relevant for lifelong cardiometabolic risk. We also provide a comprehensive picture on how metabolism develops into mature…
Publications
Publications
Blood pressure in childhood, young- and mid-adulthood: association with carotid plaque severity
Eur Heart J. 2025 Mar 25:ehaf139. doi: 10.1093/eurheartj/ehaf139. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Blood pressure (BP) is a key modifiable risk factor for atherosclerosis. How BP across different life stages associates with carotid plaque in mid-adulthood remains unclear, which is the aim of this study. METHODS: The…
Incidence of new onset arterial hypertension after metabolic bariatric surgery: an 8-year prospective follow-up with matched controls
J Hypertens. 2025 Feb 24. doi: 10.1097/HJH.0000000000003993. Online ahead of print. ABSTRACT BACKGROUND: Metabolic bariatric surgery (MBS) reduces the risk of new-onset hypertension; however, it is unclear whether this effect varies according to patient sex, age, or socioeconomic background. This study aimed to assess the risk of new-onset arterial hypertension…
Association of Paternal BMI and Diet During Pregnancy with Offspring Birth Measures: The STEPS Study
Nutrients. 2025 Feb 28;17(5):866. doi: 10.3390/nu17050866. ABSTRACT BACKGROUND/OBJECTIVES: Maternal Body Mass Index (BMI), diet quality, and their associated effects on offspring birth measures are well-established. Emerging evidence, largely from animal studies, has indicated paternal factors can influence offspring birth outcomes. However, this effect is poorly understood in humans. Our aim…
Association of neighbourhood and individual-level socioeconomic disadvantage in childhood and adulthood with cognitive function in mid-adulthood: Cardiovascular Risk in Young Finns Study
Am J Epidemiol. 2025 Mar 7:kwaf032. doi: 10.1093/aje/kwaf032. Online ahead of print. ABSTRACT Socioeconomic disadvantage at individual level is associated with poor cognitive outcomes but the link of neighbourhood disadvantage with cognitive function is unclear. We used data from Young Finns Study, a population-based cohort, to examine the associations of…
The association of childhood HDL cholesterol with atherosclerotic CVD events in adults: findings from the International Childhood Cardiovascular Cohort Consortium
Eur J Prev Cardiol. 2025 Mar 5:zwaf117. doi: 10.1093/eurjpc/zwaf117. Online ahead of print. ABSTRACT AIMS: The role of adult HDL-C in atherosclerotic cardiovascular disease (ASCVD) faces challenges from Mendelian randomisations and drug trials. However, the association between childhood HDL-C and its changes and adult ASCVD remains undefined. This study aimed…
A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations
Res Sq [Preprint]. 2025 Feb 17:rs.3.rs-6025759. doi: 10.21203/rs.3.rs-6025759/v1. ABSTRACT Background Gene-environment interactions may enhance our understanding of hypertension. Our previous study highlighted the importance of considering psychosocial factors in gene discovery for blood pressure (BP) but was limited in statistical power and population diversity. To address these challenges, we conducted…
How Blood Pressure Tracks-Salty and Secondary Causes-Reply
JAMA Pediatr. 2025 Mar 3. doi: 10.1001/jamapediatrics.2025.0045. Online ahead of print. NO ABSTRACT PMID:40029644 | DOI:10.1001/jamapediatrics.2025.0045…
Associations of 24-h Movement Behaviors With Incidence of Cardiovascular Risk Factors: The Finnish Retirement and Aging Study
Scand J Med Sci Sports. 2025 Feb;35(2):e70030. doi: 10.1111/sms.70030. ABSTRACT Low physical activity, high sedentary time (SED), and inadequate sleep increase cardiovascular disease risk, but the codependency between these 24-h movement behaviors has often been neglected. This study examined associations between 24-h movement behaviors and incidence of cardiovascular risk factors.
From Parents to Children: The Intergenerational Transference of Parents’ Sport Club Participation From Childhood to Adolescence: The 40-Year Young Finns Study
J Phys Act Health. 2025 Feb 19:1-9. doi: 10.1123/jpah.2024-0368. Online ahead of print. ABSTRACT BACKGROUND: Physical activity has been shown to transfer across generations, but more information is needed regarding the transference of different physical activity modes. This study examined (1) whether parents’ sport club participation at the ages 9-18…
