Neighbourhood socioeconomic disadvantage and the risk of preterm delivery

BMJ Paediatr Open. 2026 Apr 20;10(1):e004200. doi: 10.1136/bmjpo-2025-004200. ABSTRACT OBJECTIVE: Preterm birth is a major cause of childhood mortality and morbidity, but the aetiology of preterm delivery remains incompletely understood. We sought to examine whether cumulative exposure to neighbourhood socioeconomic disadvantage is associated with preterm delivery risk. METHODS: The association…

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Nature’s Curriculum: Genes Linked to Educational Attainment and Adult Socioeconomic Status Across Birth Cohorts in a Nordic Welfare State

Demography. 2026 Apr 20:12550847. doi: 10.1215/00703370-12550847. Online ahead of print. ABSTRACT Recent research has identified genes linked to educational attainment, but their effects on subsequent socioeconomic outcomes, particularly in egalitarian Nordic welfare states, remain largely unexplored. We analyze two genetically informed Finnish datasets, encompassing longitudinal register information on earnings, employment,…

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Pre- and postnatal maternal psychological distress and the metabolomic profile of human milk

J Nutr. 2026 Apr 16:101531. doi: 10.1016/j.tjnut.2026.101531. Online ahead of print. ABSTRACT BACKGROUND: Human milk is the gold standard of infant nutrition, providing nutrients and bioactive metabolites that shape infant immune, cognitive, and metabolic development. Maternal psychological distress, including stress, anxiety, and depression, is prevalent during the perinatal period and…

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The role of human milk oligosaccharides in shaping and restoring infant gut microbiota: Population-based cohort study

Am J Clin Nutr. 2026 Apr 16:101318. doi: 10.1016/j.ajcnut.2026.101318. Online ahead of print. ABSTRACT BACKGROUND: Infant gut microbiota colonization is important for supporting normal development and long-term health of children. Human milk oligosaccharides (HMOs) influence the composition of the gut microbiota, but their specific effects, particularly after breastfeeding, remain poorly…

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Work-related psychosocial factors and working life expectancy among Finnish public sector employees aged 50 years or older

Scand J Work Environ Health. 2026 Apr 16:4298. doi: 10.5271/sjweh.4298. Online ahead of print. ABSTRACT OBJECTIVE: This study aimed to examine the associations between work-related psychosocial factors and working life expectancy (WLE) across occupational groups among Finnish public sector employees aged ≥50 years. METHODS: In this cohort study, 70 662…

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Infant subcortical brain volumes associated with maternal obesity and diabetes: a large multicohort human study

BMC Med. 2026 Apr 16. doi: 10.1186/s12916-026-04860-6. Online ahead of print. ABSTRACT BACKGROUND: Maternal diabetes and obesity are established risk factors for adverse offspring health. Emerging evidence suggests that these fetal programming effects vary by sex, yet it remains unclear whether these factors independently or interactively influence early brain development.

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Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations

Res Sq [Preprint]. 2026 Apr 3:rs.3.rs-9283196. doi: 10.21203/rs.3.rs-9283196/v1. ABSTRACT Genetic predisposition and alcohol consumption are risk factors for increased blood pressure (BP), but their interactions influencing BP remain understudied. We conducted population-specific and cross-population meta-analyses of genome-wide gene-alcohol (GxAlc) interactions affecting BP in >1.1M individuals from multiple populations. We identified…

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