The associations of childhood and adolescence psychosocial risks with social relations in midlife

Sci Rep. 2026 Jul 1. doi: 10.1038/s41598-026-58873-5. Online ahead of print. ABSTRACT We examined whether the accumulation of psychosocial risk factors (socioeconomic risks, health behavioural risks, stressful life-events and psycho-emotional risks) in childhood and adolescence contributes to insufficient social relations (loneliness, frequency and heterogeneity of social contacts and social support)…

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Earliest age to detect lifetime cardiometabolic health stratification in children

Atherosclerosis. 2026 Jun 25;419:120833. doi: 10.1016/j.atherosclerosis.2026.120833. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Cardiovascular risk factors such as overweight and high cholesterol in childhood are predictive of high disease risk in adulthood. However, the optimal timing and scope of early prevention remains uncertain due to sparse data. Our aim…

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Retinol, Carotenoid, and Tocopherol Intake and Status, and the Risk of Islet Autoimmunity and Type 1 Diabetes: The Environmental Determinants of Diabetes in the Young Study

Diabetes Metab Res Rev. 2026 Jul;42(5):e70196. doi: 10.1002/dmrr.70196. ABSTRACT AIMS: To study the associations of dietary intake of A and E vitamins, as well as plasma retinols, carotenoids, and tocopherols in relation to development of islet autoimmunity and progression to T1D. MATERIALS AND METHODS: The Environmental Determinants of Diabetes in…

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Role of resilience in modifying the links between genetic propensity for mental disorders and irritability

J Affect Disord. 2026 Jun 25:122174. doi: 10.1016/j.jad.2026.122174. Online ahead of print. ABSTRACT AIMS: We examined (1) whether polygenic risk scores for schizophrenia (PRSSCZ), major depression (PRSMDD), and posttraumatic stress disorder (PRSPTSD) explain irritability between ages 20 and 50 and (2) whether these associations are modified by early psychosocial resilience.

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Modest Longitudinal Associations Between Parent-Reported Dental Fear at Age 5 and Child-Reported Dental Fear at Age 9: A FinnBrain Birth Cohort Study

Dent J (Basel). 2026 Jun 5;14(6):344. doi: 10.3390/dj14060344. ABSTRACT Background/Objectives: Parent report is often used to assess dental fear in early childhood, but its association with later child-reported dental fear remains unclear. This study primarily examined whether parent-reported dental fear at age 5 was associated with child-reported dental fear at…

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Whole blood epigenomic and transcriptomic characterization identifies vulnerable molecular subtypes of chronic coronary disease

Nat Commun. 2026 Jun 16. doi: 10.1038/s41467-026-73815-5. Online ahead of print. ABSTRACT Chronic coronary disease (CCD) remains a leading cause of morbidity and mortality worldwide. However, current clinical assessments, including tests of inducible ischemia or coronary artery disease severity poorly discriminate risk for future cardiovascular (CV) disease events among this…

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Effortful Control and Cortical Brain Structure in 5-Year-Old Children: Findings From the FinnBrain Birth Cohort Study

Eur J Neurosci. 2026 Jun;63(11):e70580. doi: 10.1111/ejn.70580. ABSTRACT The aim of this study was to explore the associations between an aspect of self-regulation (SR), effortful control (EC) and cortical brain structure in 5-year-old children. Efficient EC is a predictor of many attributes and important outcomes in life, such as social-emotional…

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Maternal fragmented sleep in late pregnancy is associated with higher birthweight

Eur J Obstet Gynecol Reprod Biol. 2026 May 18;324:115196. doi: 10.1016/j.ejogrb.2026.115196. Online ahead of print. ABSTRACT BACKGROUND: Sleep disturbances are common during pregnancy and tend to worsen as gestation progresses. Although poor maternal sleep has been suggested to adversely affect fetal and newborn health, existing evidence remains limited and inconsistent.

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