Sleep disturbances and sleep duration as predictors of working life expectancy among adults aged 50 years and older in Finland

Occup Environ Med. 2026 Aug 18:oemed-2025-110766. doi: 10.1136/oemed-2025-110766. Online ahead of print. ABSTRACT OBJECTIVES: To examine the associations of sleep disturbances and sleep duration with working life expectancy (WLE; the estimated number of years an individual is expected to be in the workforce) from age 50 to 68. METHODS: Data…

Read More

Father-Son Comparison of Reproductive Traits

Andrology. 2026 Aug 18. doi: 10.1111/andr.70364. Online ahead of print. ABSTRACT BACKGROUND: Little is known about the relative contribution of genetic and environmental factors on male reproductive function. OBJECTIVES: We studied in a cross-sectional setting, whether testicular function and genital size correlate in father-son pairs. The study included young men…

Read More

Structural Brain Correlates of Speech Disfluency in Early Childhood: A Dimensional Analysis in a Population-Based Cohort

Eur J Neurosci. 2026 Aug;64(4):e70652. doi: 10.1111/ejn.70652. ABSTRACT Most neuroimaging studies of speech disfluency have compared individuals who stutter with fluent controls. However, treating speech disfluency as a continuous, dimensional trait offers new insights into the neural basis of fluency during early childhood. We investigated whether naturally occurring variation in…

Read More

Longitudinal associations between sleepiness and sleep disturbances across pregnancy

Int J Gynaecol Obstet. 2026 Aug 15. doi: 10.1002/ijgo.71283. Online ahead of print. ABSTRACT OBJECTIVE: Although sleep disturbances increase during pregnancy, sleepiness does not appear to follow a similar trajectory. Given that the relationship between sleep disturbances and sleepiness during pregnancy is understudied, we examined their associations to determine whether…

Read More

Adolescent weight gain trajectories and their associations with biological aging: a genetically informed study

Int J Obes (Lond). 2026 Aug 12. doi: 10.1038/s41366-026-02194-0. Online ahead of print. ABSTRACT BACKGROUND: High body mass index (BMI) in adolescence is associated with accelerated biological aging, which might predict the onset of obesity-related diseases before they develop. Genetic factors may shape both adolescent BMI and weight trajectories. METHODS:…

Read More

Changes in toothbrushing and factors associated with less than twice daily toothbrushing by the age of four in the FinnBrain Birth Cohort Study

Acta Odontol Scand. 2026 Aug 11;85:549-558. doi: 10.2340/aos.v85.46661. ABSTRACT This study examined toothbrushing and its associated factors in children aged 1-4 years, using data from 306 mother-father-dyads and their 308 children participating in the FinnBrain Birth Cohort Study. Longitudinal multivariable regression analysis was conducted using the generalized estimating equation method…

Read More

Early life and adulthood risk factors for middle age P-wave prolongation and left atrial enlargement

Eur J Prev Cardiol. 2026 Jul 24:zwag366. doi: 10.1093/eurjpc/zwag366. Online ahead of print. ABSTRACT AIMS: P-wave prolongation and left atrial (LA) enlargement are markers of atrial cardiomyopathy and increase the risk for atrial fibrillation, stroke, and mortality. We investigated whether the cumulative burden of cardiovascular risk factors in early life…

Read More

Temporal stability of cardiometabolic risk factors from the perspective of primordial disease prevention in children

J Clin Endocrinol Metab. 2026 Jul 21:dgag285. doi: 10.1210/clinem/dgag285. Online ahead of print. ABSTRACT CONTEXT AND OBJECTIVE: Excess adiposity and circulating lipoprotein lipids in childhood are predictive of cardiometabolic disease in adulthood. We analysed temporal tracking for body mass and lipid biomarkers using population-based time-series to assess the statistical feasibility…

Read More

Genetic architecture and cross-platform validation of apolipoprotein A-IV concentrations

Genome Biol. 2026 Jul 14. doi: 10.1186/s13059-026-04196-7. Online ahead of print. ABSTRACT BACKGROUND: Apolipoprotein A-IV (apoA-IV) plays key roles in lipid metabolism, reverse cholesterol transport, and kidney function, yet its genetic determinants remain poorly defined. We conduct a genome-wide association study (GWAS) meta-analysis of apoA-IV concentrations measured by ELISA in…

Read More

Effect of dietary counselling on educational disparities in cardiometabolic health from childhood to adulthood

Eur J Prev Cardiol. 2026 Jul 15:zwag355. doi: 10.1093/eurjpc/zwag355. Online ahead of print. ABSTRACT AIM: We examined whether parental education was associated with long-term cardiometabolic health and whether the effectiveness of a dietary counselling intervention differed by parental education level, hypothesizing greater effectiveness among highly educated families. METHODS: The study…

Read More
utu logo vsshp logo