Publications

Acta Paediatr. 2024 Nov 1. doi: 10.1111/apa.17479. Online ahead of print. ABSTRACT AIM: This study aimed to assess the cognitive development of individuals with congenital hypothyroidism. METHODS: Using hospital records, we identified 180 patients with congenital hypothyroidism born between 1980 and 2018 in Turku and Kuopio University Hospital catchment areas.

Biosci Rep. 2024 Oct 30:BSR20240763. doi: 10.1042/BSR20240763. Online ahead of print. ABSTRACT Early-onset pre-eclampsia is believed to arise from defective placentation in the 1st trimester, leading to placental ischaemia/reperfusion (I/R) and oxidative stress. However, our current understanding of the effects of I/R and oxidative stress on trophoblast function is ambiguous…

Scand J Med Sci Sports. 2024 Nov;34(11):e14751. doi: 10.1111/sms.14751. ABSTRACT There is scarcity of studies using device-based measures to examine how relationship and parenthood transitions modify 24-h movement behaviors. This study examined how the composition of 24-h movement behaviors changes during these life transitions. Young adults (n = 170, mean…

Sci Rep. 2024 Oct 26;14(1):25463. doi: 10.1038/s41598-024-75496-w. ABSTRACT Season of birth, viral infections, HLA haplogenotypes and non-HLA variants are implicated in the development of celiac disease and celiac disease autoimmunity, suggesting a combined role of genes and environmental exposures. The aim of the study was to further decipher the biological…

Aging Cell. 2024 Oct 25:e14394. doi: 10.1111/acel.14394. Online ahead of print. ABSTRACT Evidence is accumulating on the connection of early adversities and harsh family environment with epigenetic ageing. We investigated whether early psychosocial resilience is associated with epigenetic ageing in adulthood. We used the population-based Young Finns data (n =…

Entropy (Basel). 2024 Sep 30;26(10):837. doi: 10.3390/e26100837. ABSTRACT Higher-order relationships are a central concept in the science of complex systems. A popular method of attempting to estimate the higher-order relationships of synergy and redundancy from data is through the O-information. It is an information-theoretic measure composed of Shannon entropy terms…

Andrology. 2024 Oct 18. doi: 10.1111/andr.13777. Online ahead of print. ABSTRACT BACKGROUND: Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib-treated male patients…

Pediatrics. 2024 Oct 14:e2024066736. doi: 10.1542/peds.2024-066736. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVES: Childhood risk factors are associated with cardiovascular events in adulthood. We compared the utility of a risk model based solely on nonlaboratory risk factors in adolescence versus a model that additionally included lipids to predict cardiovascular…

J Epidemiol Community Health. 2024 Oct 1:jech-2024-222690. doi: 10.1136/jech-2024-222690. Online ahead of print. ABSTRACT BACKGROUND: The transition to retirement is a significant turning point in life, which may lead to changes in food habits. OBJECTIVE: To examine changes in red meat, fish, vegetables and fruit consumption during the retirement transition…

Eur J Pediatr. 2024 Sep 28. doi: 10.1007/s00431-024-05775-1. Online ahead of print. ABSTRACT Antibiotics are frequently administered in the neonatal period and early infancy. Little is known about the long-term health consequences of early life antibiotic exposure. The objective is to investigate the association between neonatal and early life (0-6…