Semin Reprod Med. 2023 Nov;41(6):226-240. doi: 10.1055/s-0044-1782151. Epub 2024 Mar 18. ABSTRACT Since the end of the last century, several reports have suggested that semen quality is declining, especially in Western countries. Furthermore, cross-sectional studies using similar protocols have suggested regional differences in semen quality of young and fertile men.
Publications
Publications
A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations
medRxiv [Preprint]. 2024 Mar 8:2024.03.07.24303870. doi: 10.1101/2024.03.07.24303870. ABSTRACT Although both short and long sleep duration are associated with elevated hypertension risk, our understanding of their interplay with biological pathways governing blood pressure remains limited. To address this, we carried out genome-wide cross-population gene-by-short-sleep and long-sleep duration interaction analyses for three…
Pubertal testicular volume references for ruler, orchidometer, and ultrasonography measurements based on a longitudinal follow-up
Andrology. 2024 Mar 14. doi: 10.1111/andr.13629. Online ahead of print. ABSTRACT BACKGROUND: Testicular volume is a marker of male pubertal development. Various clinical conditions and their treatments may influence testicular growth. OBJECTIVES: To create ruler-based age-dependent pubertal testicular volume references that enable calculation of standard deviation (SD) scores. MATERIALS AND…
Associations between arterial health and sexual function in women aged 60-64 years
Acta Obstet Gynecol Scand. 2024 Mar 14. doi: 10.1111/aogs.14826. Online ahead of print. ABSTRACT INTRODUCTION: Female sexual dysfunction is very common, but its determinants remain under-investigated. Vasculogenic impairments are suggested to be related to female sexual dysfunction, but previous literature regarding the association is scarce. This study aims to study…
Relationship of device measured physical activity type and posture with cardiometabolic health markers: pooled dose-response associations from the Prospective Physical Activity, Sitting and Sleep Consortium
Diabetologia. 2024 Mar 13. doi: 10.1007/s00125-024-06090-y. Online ahead of print. ABSTRACT AIMS/HYPOTHESIS: The aim of this study was to examine the dose-response associations of device-measured physical activity types and postures (sitting and standing time) with cardiometabolic health. METHODS: We conducted an individual participant harmonised meta-analysis of 12,095 adults (mean ±…
Are changes in sleep problems associated with changes in life satisfaction during the retirement transition?
Eur J Ageing. 2024 Mar 12;21(1):7. doi: 10.1007/s10433-024-00802-4. ABSTRACT Retirement reduces sleep problems, but changes in life satisfaction during the retirement transition are multifactorial and partly unknown. The aim of this prospective cohort study was to examine whether changes in sleep problems are associated with changes in total and domain-specific…
Association of childhood socioeconomic status with adulthood maximal exercise blood pressure: the Cardiovascular Risk in Young Finns Study
Blood Press. 2024 Dec;33(1):2323987. doi: 10.1080/08037051.2024.2323987. Epub 2024 Mar 11. ABSTRACT PURPOSE: Socioeconomic status has been related to resting blood pressure (BP) levels at different stages of life. However, the association of childhood socioeconomic status (SES) and adulthood exercise BP is largely unknown. Therefore, we studied the association of childhood…
Genome-wide characterization of circulating metabolic biomarkers
Nature. 2024 Mar 6. doi: 10.1038/s41586-024-07148-y. Online ahead of print. ABSTRACT Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism1-7. This detailed knowledge of the genetic determinants of systemic metabolism has been pivotal for uncovering how genetic pathways influence biological mechanisms…
Intergenerational continuity of loneliness and potential mechanisms: Young Finns Multigenerational Study
Sci Rep. 2024 Mar 5;14(1):5465. doi: 10.1038/s41598-024-56147-6. ABSTRACT Evidence on the intergenerational continuity of loneliness and on potential mechanisms that connect loneliness across successive generations is limited. We examined the association between loneliness of (G0) parents (859 mothers and 570 fathers, mean age 74 years) and their children (G1) (433…
A healthy lifestyle can support future sexual satisfaction: results from a 9-year longitudinal survey
J Sex Med. 2024 Mar 5:qdae009. doi: 10.1093/jsxmed/qdae009. Online ahead of print. ABSTRACT BACKGROUND: Previous follow-up studies have demonstrated the association between good health behavior and good sexual functioning for men, but the longitudinal relationship between multiple health behaviors and satisfaction with sex life remains understudied. AIM: The aim of…
