PLoS One. 2024 Feb 23;19(2):e0297594. doi: 10.1371/journal.pone.0297594. eCollection 2024. ABSTRACT A striking global health development over the past few decades has been the increasing prevalence of overweight and obesity. At the same time, depression has become increasingly common in almost all high-income countries. We investigated whether body weight, measured by…
Publications
Publications
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes
Diabetes Metab Res Rev. 2024 Feb;40(2):e3777. doi: 10.1002/dmrr.3777. ABSTRACT BACKGROUND/AIM: Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta-cell antigens, preceding clinical diagnosis by a period of preclinical disease activity. As screening activity to identify autoantibody-positive individuals increases, a rise in presymptomatic…
Infant feeding-a scoping review for Nordic Nutrition Recommendations 2023
Food Nutr Res. 2024 Feb 5;68. doi: 10.29219/fnr.v68.10456. eCollection 2024. ABSTRACT The 2012 edition of the Nordic Nutrition Recommendations (NNR) included recommendations on breastfeeding, based on the most recent guidelines and recommendations from major national food and health authorities and organizations, systematic reviews, and some original research. For NNR 2023,…
Antecedents of maternal pregnancy-related anxiety trajectories: The FinnBrain birth cohort study
Acta Psychiatr Scand. 2024 Feb 18. doi: 10.1111/acps.13671. Online ahead of print. ABSTRACT OBJECTIVE: Little is known about the normative courses of pregnancy-related anxiety throughout pregnancy and their antecedents. We examined in a large scale pregnancy cohort which potentially distinct trajectories of pregnancy-related anxiety across pregnancy can be identified, and…
Small Non-Coding RNAs in Male Reproduction
Semin Reprod Med. 2024 Feb 12. doi: 10.1055/s-0044-1779726. Online ahead of print. ABSTRACT Male reproductive functions are strictly regulated in order to maintain sperm production and fertility. All processes are controlled by precise regulation of gene expression, which creates specific gene expression programs for different developmental stages and cell types,…
Correction to: Tracking of apolipoprotein B levels measured in childhood and adolescence: systematic review and meta-analysis
Eur J Pediatr. 2024 Jan 31. doi: 10.1007/s00431-024-05445-2. Online ahead of print. NO ABSTRACT PMID:38294516 | DOI:10.1007/s00431-024-05445-2…
Metabolic syndrome and epigenetic aging: a twin study
Int J Obes (Lond). 2024 Jan 25. doi: 10.1038/s41366-024-01466-x. Online ahead of print. ABSTRACT BACKGROUND: Metabolic syndrome (MetS) is associated with premature aging, but whether this association is driven by genetic or lifestyle factors remains unclear. METHODS: Two independent discovery cohorts, consisting of twins and unrelated individuals, were examined (N…
Negative associations between maternal prenatal hair cortisol and child socioemotional problems
Psychoneuroendocrinology. 2024 Jan 4;162:106955. doi: 10.1016/j.psyneuen.2023.106955. Online ahead of print. ABSTRACT Maternal prenatal distress can participate in the programming of offspring development, in which exposure to altered maternal long-term cortisol levels as measured by hair cortisol concentrations (HCC) may contribute. Yet, studies investigating whether and how maternal prenatal HCC associates…
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements
Nat Commun. 2024 Jan 18;15(1):586. doi: 10.1038/s41467-024-44709-1. ABSTRACT X-chromosomal genetic variants are understudied but can yield valuable insights into sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry X-chromosome-wide association meta-analysis of seven kidney-related traits (n = 908,697), identifying 23 loci genome-wide significantly associated with two of the…
Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes
Genome Biol. 2024 Jan 16;25(1):22. doi: 10.1186/s13059-023-03136-z. ABSTRACT BACKGROUND: Pubertal growth patterns correlate with future health outcomes. However, the genetic mechanisms mediating growth trajectories remain largely unknown. Here, we modeled longitudinal height growth with Super-Imposition by Translation And Rotation (SITAR) growth curve analysis on ~ 56,000 trans-ancestry samples with repeated…
